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青少年摄入牛奶(而非全部乳制品、酸奶或奶酪)与心血管代谢危险因素聚集呈负相关。

Intake of milk, but not total dairy, yogurt, or cheese, is negatively associated with the clustering of cardiometabolic risk factors in adolescents.

作者信息

Abreu Sandra, Moreira Pedro, Moreira Carla, Mota Jorge, Moreira-Silva Isabel, Santos Paula-Clara, Santos Rute

机构信息

Research Centre in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, 91-4200 Porto, Portugal.

Research Centre in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, 91-4200 Porto, Portugal; Faculty of Nutrition and Food Science, University of Porto, Porto, 91-4200 Porto, Portugal.

出版信息

Nutr Res. 2014 Jan;34(1):48-57. doi: 10.1016/j.nutres.2013.10.008. Epub 2013 Oct 24.

Abstract

Epidemiologic studies have reported an inverse association between dairy product consumption and cardiometabolic risk factors in adults, but this relation is relatively unexplored in adolescents. We hypothesized that a higher dairy product intake is associated with lower cardiometabolic risk factor clustering in adolescents. To test this hypothesis, a cross-sectional study was conducted with 494 adolescents aged 15 to 18 years from the Azorean Archipelago, Portugal. We measured fasting glucose, insulin, total cholesterol, high-density lipoprotein cholesterol, triglycerides, systolic blood pressure, body fat, and cardiorespiratory fitness. We also calculated homeostatic model assessment and total cholesterol/high-density lipoprotein cholesterol ratio. For each one of these variables, a z score was computed using age and sex. A cardiometabolic risk score (CMRS) was constructed by summing up the z scores of all individual risk factors. High risk was considered to exist when an individual had at least 1 SD from this score. Diet was evaluated using a food frequency questionnaire, and the intake of total dairy (included milk, yogurt, and cheese), milk, yogurt, and cheese was categorized as low (equal to or below the median of the total sample) or "appropriate" (above the median of the total sample).The association between dairy product intake and CMRS was evaluated using separate logistic regression, and the results were adjusted for confounders. Adolescents with high milk intake had lower CMRS, compared with those with low intake (10.6% vs 18.1%, P = .018). Adolescents with appropriate milk intake were less likely to have high CMRS than those with low milk intake (odds ratio, 0.531; 95% confidence interval, 0.302-0.931). No association was found between CMRS and total dairy, yogurt, and cheese intake. Only milk intake seems to be inversely related to CMRS in adolescents.

摘要

流行病学研究报告称,成年人乳制品消费与心脏代谢风险因素之间存在负相关,但这种关系在青少年中相对未被充分研究。我们假设,较高的乳制品摄入量与青少年较低的心脏代谢风险因素聚集有关。为了验证这一假设,我们对来自葡萄牙亚速尔群岛的494名15至18岁青少年进行了一项横断面研究。我们测量了空腹血糖、胰岛素、总胆固醇、高密度脂蛋白胆固醇、甘油三酯、收缩压、体脂和心肺适能。我们还计算了稳态模型评估和总胆固醇/高密度脂蛋白胆固醇比值。对于这些变量中的每一个,使用年龄和性别计算z分数。通过将所有个体风险因素的z分数相加构建心脏代谢风险评分(CMRS)。当个体的该评分至少偏离1个标准差时,认为存在高风险。使用食物频率问卷评估饮食,并将总乳制品(包括牛奶、酸奶和奶酪)、牛奶、酸奶和奶酪的摄入量分为低(等于或低于总样本中位数)或“适当”(高于总样本中位数)。使用单独的逻辑回归评估乳制品摄入量与CMRS之间的关联,并对结果进行混杂因素调整。与低牛奶摄入量的青少年相比,高牛奶摄入量的青少年CMRS较低(10.6%对18.1%,P = 0.018)。与低牛奶摄入量的青少年相比,牛奶摄入量适当的青少年患高CMRS的可能性较小(优势比,0.531;95%置信区间,0.302 - 0.931)。未发现CMRS与总乳制品、酸奶和奶酪摄入量之间存在关联。在青少年中,似乎只有牛奶摄入量与CMRS呈负相关。

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