《Cache 县老龄化记忆研究：阿尔茨海默病发病后影响其风险和进展的因素》
The Cache County Study on Memory in Aging: factors affecting risk of Alzheimer's disease and its progression after onset.
机构信息
Department of Psychology, Utah State University , Logan, UT.
出版信息
Int Rev Psychiatry. 2013 Dec;25(6):673-85. doi: 10.3109/09540261.2013.849663.
Abstract
The Cache County Study on Memory in Aging is a longitudinal, population-based study of Alzheimer's disease (AD) and other dementias. Initiated in 1995 and extending to 2013, the study has followed over 5,000 elderly residents of Cache County, Utah (USA) for over twelve years. Achieving a 90% participation rate at enrolment, and spawning two ancillary projects, the study has contributed to the literature on genetic, psychosocial and environmental risk factors for AD, late-life cognitive decline, and the clinical progression of dementia after its onset. This paper describes the major study contributions to the literature on AD and dementia.
摘要
《老龄化记忆的 Cache 县研究》是一项针对阿尔茨海默病（AD）和其他痴呆症的纵向、基于人群的研究。该研究始于 1995 年，一直持续到 2013 年，跟踪了犹他州 Cache 县的 5000 多名老年居民超过 12 年。该研究在入组时实现了 90%的参与率，并衍生出了两个辅助项目，为 AD、晚年认知能力下降以及发病后痴呆症的临床进展的遗传、心理社会和环境风险因素的文献做出了贡献。本文介绍了该研究对 AD 和痴呆症文献的主要贡献。
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