Lima-Oliveira Gabriel, Lippi Giuseppe, Salvagno Gian Luca, Montagnana Martina, Picheth Geraldo, Guidi Gian Cesare
Laboratory of Clinical Biochemistry, Department of Life and Reproduction Sciences, University of Verona, Ospedale Policlinico, P.le L.A. Scuro, 37134 Verona, Italy ; Post-Graduate Program of Pharmaceutical Sciences, Department of Medical Pathology, Federal University of Parana, Curitiba, Parana Brazil ; MERCOSUL, Sector Committee of Clinical Analyses and in vitro Diagnostics, CSM 20, Rio de Janeiro, Brazil ; Brazilian Society of Clinical Analyses on Sao Paulo State, Sao Paulo, Brazil.
Laboratory of Clinical Chemistry and Hematology, Department of Pathology and Laboratory Medicine, Academic Hospital of Parma, Parma, Italy.
Indian J Clin Biochem. 2013 Jul;28(3):235-41. doi: 10.1007/s12291-013-0319-y. Epub 2013 Apr 3.
A new device called Buzzy(®) has been recently presented that combines a cooling ice pack and a vibrating motor in order to relieve the venipuncture pain. The aim of this study was to evaluate the impact of Buzzy(®) use during diagnostic blood specimen collection by venipuncture for routine immunochemistry tests. Blood was collected from 100 volunteers by a single, expert phlebotomist. A vein was located on the left forearm without applying tourniquet, in order to prevent any interference from venous stasis, and blood samples were collected using a 20-G straight needle directly into 5 mL vacuum tubes with clot activator and gel separator. In sequence, external cold and vibration by Buzzy(®) was applied on the right forearm-5 cm above the chosen puncture site-for 1 min before venipuncture and continued until the end of the same procedure already done in the left forearm. The panel of tests included the following: glucose, total cholesterol, HDL-cholesterol, triglycerides, total protein, albumin, c-reactive protein, urea, creatinine, uric acid, alkaline phosphatase, amylase, AST, ALT, g-glutamyltransferase, lactate dehydrogenase, creatine kinase, total bilirubin, phosphorus, calcium, magnesium, iron, sodium, potassium, chloride, lipase, cortisol, insulin, thyroid-stimulating hormone, total triiodothyronine, free triiodothyronine, total thyroxine, free thyroxine and haemolysis index. Clinically significant differences between samples were found only for: total protein, albumin and transferrin. The Buzzy(®) can be used during diagnostic blood specimens collection by venipuncture for the majority of the routine immunochemistry tests. We only suggest avoiding this device during blood collection when protein, albumin and transferrin determinations should be performed.
最近推出了一种名为Buzzy(®)的新设备,它结合了冷敷冰袋和振动电机,以减轻静脉穿刺疼痛。本研究的目的是评估在常规免疫化学检测的静脉穿刺采集诊断血标本过程中使用Buzzy(®)的影响。由一名专业采血师从100名志愿者身上采集血液。在不使用止血带的情况下,于左前臂找到一条静脉,以防止静脉淤滞的任何干扰,然后使用20G直针直接将血样采集到含有促凝剂和凝胶分离剂的5 mL真空管中。依次在静脉穿刺前1分钟,将Buzzy(®)产生的外部冷感和振动作用于右前臂——选定穿刺部位上方5 cm处——并持续到左前臂相同操作结束。检测项目包括:葡萄糖、总胆固醇、高密度脂蛋白胆固醇、甘油三酯、总蛋白、白蛋白、c反应蛋白、尿素、肌酐、尿酸、碱性磷酸酶、淀粉酶、谷草转氨酶、谷丙转氨酶、γ-谷氨酰转移酶、乳酸脱氢酶、肌酸激酶、总胆红素、磷、钙、镁、铁、钠、钾、氯、脂肪酶、皮质醇、胰岛素、促甲状腺激素、总三碘甲状腺原氨酸、游离三碘甲状腺原氨酸、总甲状腺素、游离甲状腺素和溶血指数。仅在总蛋白、白蛋白和转铁蛋白方面发现样本之间存在临床显著差异。Buzzy(®)可用于大多数常规免疫化学检测的静脉穿刺采集诊断血标本过程中。我们仅建议在需要检测蛋白、白蛋白和转铁蛋白时采血过程中避免使用该设备。