Lee Jae Hyup, Lee Dong-Oh, Lee Ji-Ho, Lee Hyeong-Seok
Department of Orthopedic Surgery, College of Medicine, Seoul National University, Seoul 110-744, Korea; Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University, Seoul 110-744, Korea; Department of Orthopedic Surgery, SMG-SNU Boramae Medical Center, 425 Shindaebang-2-Dong, Seoul 156-707, Korea.
Department of Orthopedic Surgery, SMG-SNU Boramae Medical Center, 425 Shindaebang-2-Dong, Seoul 156-707, Korea.
Spine J. 2014 Oct 1;14(10):2281-9. doi: 10.1016/j.spinee.2014.01.028. Epub 2014 Jan 23.
Percutaneous kyphoplasty is effective for pain reduction and vertebral height restoration in patients with osteoporotic vertebral fractures. However, in cases of severely collapsed fractures involving the loss of more than 70% of the vertebral height, kyphoplasty is technically difficult to perform and the outcomes remain unknown.
To compare the vertebral height restoration rate, kyphotic angle, and clinical results of patients who underwent kyphoplasty according to the degree of anterior vertebral height loss. In addition, to determine the feasibility and effects of kyphoplasty on severely collapsed osteoporotic vertebral fractures.
STUDY DESIGN/SETTING: A retrospective study.
A total of 129 patients (145 vertebrae) who underwent kyphoplasty for osteoporotic painful vertebral fracture and followed up for more than 1 year between September 2005 and August 2012 were recruited for the analysis.
The patients' kyphotic angle, anterior vertebral height, and anterior vertebral height restoration ratio 1 year after surgery were compared. Pre- and postoperative pain around the fractured vertebra and the radiological and clinical results according to bone mineral density (BMD) were also compared.
Patients were divided into three groups for comparison, according to radiographic findings. Patients with an anterior height compression ratio more than 70% at the time of fracture comprised Group I, patients with a compression ratio of 50-70% comprised Group II, and those with a compression ratio of 30-50% comprised Group III.
Group I showed a greater extent of anterior height restoration immediately after surgery compared with the other groups, which noticeably decreased over time. All three groups showed significant restoration of the anterior vertebral height between pre- and postoperative values. The anterior vertebral height 1 year after surgery did not differ between Group I and Group II but was significantly higher in Group III. There was no correlation between the BMD and restoration or decrease of anterior vertebral height over time. Pain around the fractured vertebra significantly decreased in all groups immediately and 1 year after surgery compared with preoperative levels, although the pain level 1 year after surgery did not differ significantly between the groups.
In patients with an anterior vertebral compression ratio more than 70% because of osteoporotic vertebral fracture, although the anterior height and kyphotic angle were significantly lower than those of patients with an anterior vertebral compression ratio of 30% to 50%, kyphoplasty significantly improved the degree of pain, restored the anterior vertebral height, and maintained the kyphotic angle. Therefore, kyphoplasty can be a useful approach in patients with an anterior vertebral compression ratio more than 70%.
经皮椎体后凸成形术在治疗骨质疏松性椎体骨折患者的疼痛缓解和椎体高度恢复方面是有效的。然而,在严重塌陷骨折且椎体高度丢失超过70%的病例中,椎体后凸成形术在技术上难以实施,其效果仍不明确。
根据椎体前缘高度丢失程度比较接受椎体后凸成形术患者的椎体高度恢复率、后凸角和临床结果。此外,确定椎体后凸成形术治疗严重塌陷骨质疏松性椎体骨折的可行性和效果。
研究设计/地点:一项回顾性研究。
选取2005年9月至2012年8月间因骨质疏松性疼痛性椎体骨折接受椎体后凸成形术并随访1年以上的129例患者(145个椎体)进行分析。
比较患者术后1年的后凸角、椎体前缘高度和椎体前缘高度恢复率。还比较了骨折椎体周围术前和术后的疼痛情况以及根据骨密度(BMD)得出的影像学和临床结果。
根据影像学检查结果将患者分为三组进行比较。骨折时椎体前缘高度压缩率超过70%的患者为I组,压缩率为50%-70%的患者为II组,压缩率为30%-50%的患者为III组。
与其他组相比,I组术后即刻椎体前缘高度恢复程度更大,但随时间明显降低。所有三组术前和术后椎体前缘高度均有显著恢复。I组和II组术后1年的椎体前缘高度无差异,但III组显著更高。骨密度与椎体前缘高度随时间的恢复或降低之间无相关性。与术前水平相比,所有组骨折椎体周围的疼痛在术后即刻和术后1年均显著减轻,尽管术后1年各组间疼痛水平无显著差异。
在因骨质疏松性椎体骨折导致椎体前缘压缩率超过70%的患者中,尽管椎体前缘高度和后凸角显著低于椎体前缘压缩率为30%至50%的患者,但椎体后凸成形术显著改善了疼痛程度,恢复了椎体前缘高度,并维持了后凸角。因此,椎体后凸成形术对于椎体前缘压缩率超过70%的患者可能是一种有用的治疗方法。