Sanz-Martin Araceli, Hernández-González Marisela, Guevara Miguel Ángel, Santana Gloria, Gumá-Díaz Emilio
Universidad de Guadalajara, Guadalajara, Mexico.
Rev Neurol. 2014 Feb 1;58(3):103-12.
The metabolism of alcohol and cognitive functions can vary during the menstrual cycle. Also, both alcohol ingestion and hormonal variations during menstruation have been associated with characteristic changes in electroencephalographic (EEG) activity. AIM. To determine whether EEG activity during a working memory task is affected by acute alcohol consumption, and if these EEG patterns vary in relation to different phases of the menstrual cycle.
24 women who drank a moderate dose of alcohol or placebo during the follicular and early luteal phases of the menstrual cycle. The EEG activity was recorded during performance of viso-spatial working memory task.
Although the alcohol did not deteriorate the performance of working memory task, it caused in the EEG a decrease of relative theta power and lower right fronto-parietal correlation in theta and alpha2 bands. Only women who drank alcohol in the follicular phase had a higher relative potency of alpha1, which could indicate a lower level of arousal and attention.
These results contribute to a better understanding of the brain mechanisms underlying cognitive changes with alcohol and its relationship to the menstrual cycle.
酒精代谢和认知功能在月经周期中可能会有所不同。此外，月经期间饮酒和激素变化均与脑电图（EEG）活动的特征性变化有关。目的：确定工作记忆任务期间的EEG活动是否受急性酒精摄入的影响，以及这些EEG模式是否因月经周期的不同阶段而有所变化。
24名女性在月经周期的卵泡期和黄体早期饮用适量酒精或安慰剂。在执行视觉空间工作记忆任务期间记录EEG活动。
尽管酒精并未降低工作记忆任务的表现，但它导致EEG中相对θ波功率降低，且θ波和α2波频段的右下额顶叶相关性降低。只有在卵泡期饮酒的女性具有较高的α1相对功率，这可能表明其觉醒和注意力水平较低。
这些结果有助于更好地理解酒精导致认知变化的脑机制及其与月经周期的关系。
