使用商用三维二极管阵列对3种不同治疗计划和交付复杂性水平进行控制点分析比较。
Control point analysis comparison for 3 different treatment planning and delivery complexity levels using a commercial 3-dimensional diode array.
作者信息
Abdellatif Ady, Gaede Stewart
机构信息
Department of Physics and Engineering, London Regional Cancer Program, London, Ontario, Canada.
Department of Physics and Engineering, London Regional Cancer Program, London, Ontario, Canada; Department of Oncology, Western University, London, Ontario, Canada; Department of Medical Biophysics, Western University, London, Ontario, Canada.
出版信息
Med Dosim. 2014 Summer;39(2):174-9. doi: 10.1016/j.meddos.2013.12.005. Epub 2014 Jan 27.
To investigate the use of "Control Point Analysis" (Sun Nuclear Corporation, Melbourne, FL) to analyze and compare delivered volumetric-modulated arc therapy (VMAT) plans for 3 different treatment planning complexity levels. A total of 30 patients were chosen and fully anonymized for the purpose of this study. Overall, 10 lung stereotactic body radiotherapy (SBRT), 10 head-and-neck (H&N), and 10 prostate VMAT plans were generated on Pinnacle(3) and delivered on a Varian linear accelerator (LINAC). The delivered dose was measured using ArcCHECK (Sun Nuclear Corporation, Melbourne, FL). Each plan was analyzed using "Sun Nuclear Corporation (SNC) Patient 6" and "Control Point Analysis." Gamma passing percentage was used to assess the differences between the measured and planned dose distributions and to assess the role of various control point binning combinations. Of the different sites considered, the prostate cases reported the highest gamma passing percentages calculated with "SNC Patient 6" (97.5% to 99.2% for the 3%, 3mm) and "Control Point Analysis" (95.4% to 98.3% for the 3%, 3mm). The mean percentage of passing control point sectors for the prostate cases increased from 51.8 ± 7.8% for individual control points to 70.6 ± 10.5% for 5 control points binned together to 87.8 ± 11.0% for 10 control points binned together (2%, 2-mm passing criteria). Overall, there was an increasing trend in the percentage of sectors passing gamma analysis with an increase in the number of control points binned together in a sector for both the gamma passing criteria (2%, 2mm and 3%, 3mm). Although many plans passed the clinical quality assurance criteria, plans involving the delivery of high Monitor Unit (MU)/control point (SBRT) and plans involving high degree of modulation (H&N) showed less delivery accuracy per control point compared with plans with low MU/control point and low degree of modulation (prostate).
为研究使用“控制点分析”（佛罗里达州墨尔本太阳核公司）来分析和比较针对3种不同治疗计划复杂程度生成的容积调强弧形放疗（VMAT）计划。本研究共选取30例患者并进行了完全匿名处理。总体而言，在Pinnacle(3)上生成了10例肺部立体定向体部放疗（SBRT）、10例头颈部（H&N）和10例前列腺VMAT计划，并在瓦里安直线加速器（LINAC）上进行了交付。使用ArcCHECK（佛罗里达州墨尔本太阳核公司）测量交付剂量。每个计划均使用“太阳核公司（SNC）患者6”和“控制点分析”进行分析。伽马通过率用于评估测量剂量分布与计划剂量分布之间的差异，并评估各种控制点分组组合的作用。在所考虑的不同部位中，前列腺病例在使用“SNC患者6”计算时报告的伽马通过率最高（3%、3毫米时为97.5%至99.2%），使用“控制点分析”时（3%、3毫米时为95.4%至98.3%）。前列腺病例通过控制点扇区的平均百分比从单个控制点的51.8±7.8%增加到5个控制点合并时的70.6±10.5%，再增加到10个控制点合并时的87.8±11.0%（2%、2毫米通过标准）。总体而言，对于两种伽马通过标准（2%、2毫米和3%、3毫米），随着扇区内合并控制点数量的增加，通过伽马分析的扇区百分比呈上升趋势。尽管许多计划通过了临床质量保证标准，但与低监测单位（MU）/控制点和低调制程度（前列腺）的计划相比，涉及高MU/控制点（SBRT）交付的计划和涉及高调制程度（H&N）的计划每个控制点的交付准确性较低。
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