Cognitive Perceptual and Brain Sciences, University College London, London, UK; Department of Psychological Sciences, Birkbeck/UCL Centre for NeuroImaging (BUCNI), Birkbeck College, University of London, London, UK.
Institute for Neural Computation, University of California San Diego, La Jolla, CA, United States.
Curr Opin Neurobiol. 2014 Feb;24(1):39-46. doi: 10.1016/j.conb.2013.08.014. Epub 2013 Oct 2.
Parietal cortex has long been known to be a site of sensorimotor integration. Recent findings in humans have shown that it is divided up into a number of small areas somewhat specialized for eye movements, reaching, and hand movements, but also face-related movements (avoidance, eating), lower body movements, and movements coordinating multiple body parts. The majority of these areas contain rough sensory (receptotopic) maps, including a substantial multisensory representation of the lower body and lower visual field immediately medial to face VIP. There is strong evidence for retinotopic remapping in LIP and face-centered remapping in VIP, and weaker evidence for hand-centered remapping. The larger size of the functionally distinct inferior parietal default mode network in humans compared to monkeys results in a superior and medial displacement of middle parietal areas (e.g., the saccade-related LIP's). Multisensory superior parietal areas located anterior to the angular gyrus such as AIP and VIP are less medially displaced relative to macaque monkeys, so that human LIP paradoxically ends up medial to human VIP.
顶叶皮层一直以来都被认为是感觉运动整合的部位。最近在人类身上的发现表明,它被分为几个较小的区域,这些区域在眼动、伸手和手部运动方面略有专业化,但也与面部运动(回避、进食)、下肢运动和协调多个身体部位的运动有关。这些区域中的大多数都包含粗糙的感觉(接受体定位)图,包括对下肢和下视野的大量多感觉表示,其位于脸 VIP 区域的正内侧。在 LIP 中存在强烈的视网膜映射重新映射的证据,在 VIP 中存在面孔中心的重新映射的证据,而在手部中心的重新映射的证据较弱。与猴子相比,人类功能上不同的下顶叶默认模式网络的较大尺寸导致中顶叶区域(例如与扫视相关的 LIP)向上和向内侧位移。位于角回前部的多感觉上顶叶区域,如 AIP 和 VIP,相对于猕猴的向内侧位移较小,因此人类的 LIP 反常地位于人类 VIP 的内侧。