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产后抑郁症筛查——当前知识总结

Screening for postnatal depression--a summary of current knowledge.

作者信息

Eberhard-Gran Malin, Slinning Kari, Rognerud Marit

出版信息

Tidsskr Nor Laegeforen. 2014 Feb 11;134(3):297-301. doi: 10.4045/tidsskr.13.0068.

Abstract

BACKGROUND

Screening for postnatal depression using the Edinburgh Postnatal Depression Scale (EPDS), in combination with counselling sessions with a public health nurse (the Edinburgh method), has been introduced at many child health centres in Norway. In this article we provide a summary of the existing knowledge of how postnatal depression should be handled, with a particular emphasis on the benefits of screening.

MATERIAL AND METHOD

A literature search was conducted in PubMed, PsychInfo and Cochrane. National and international guidelines and related reports were downloaded from the websites of the respective health authorities.

RESULTS

Depressive symptoms occur in 10-15% of all new mothers. Several international studies have demonstrated a positive effect of the Edinburgh method, and screening for postnatal depression is recommended in a number of countries. In Norway no studies have yet been conducted to assess efficacy and resource use. The EPDS scale has been validated in several countries, and in a Norwegian validation study various threshold values for EPDS scores were compared with DSM-IV criteria for «major depression». Total score on the EPDS scale varies from 0 to 30. A threshold value of 10 yielded a sensitivity of 100% and a specificity of 87%, which resulted in many false positives. Higher threshold values yielded significantly lower sensitivity (67%). Two EPDS measurements plus an interview have been recommended, but have as yet been insufficiently tested.

INTERPRETATION

Screening for postnatal depression may be an appropriate measure. However, further knowledge is needed about the efficacy in Norway of the Edinburgh method and other models for follow-up, as well as agreement on the cut-off point for a positive test.

摘要

背景

挪威的许多儿童健康中心已采用爱丁堡产后抑郁量表(EPDS)结合与公共卫生护士的咨询服务(爱丁堡方法)来筛查产后抑郁症。在本文中,我们总结了关于如何应对产后抑郁症的现有知识,特别强调了筛查的益处。

材料与方法

在PubMed、PsychInfo和Cochrane数据库中进行了文献检索。从各自卫生当局的网站下载了国家和国际指南及相关报告。

结果

所有新妈妈中有10% - 15%出现抑郁症状。多项国际研究证明了爱丁堡方法的积极效果,一些国家推荐对产后抑郁症进行筛查。挪威尚未开展评估其疗效和资源利用情况的研究。EPDS量表已在多个国家得到验证,在一项挪威验证研究中,将EPDS分数的不同阈值与DSM - IV标准下的“重度抑郁症”进行了比较。EPDS量表的总分从0到30分不等。阈值为10时,灵敏度为100%,特异度为87%,这导致出现许多假阳性结果。较高的阈值产生的灵敏度显著较低(67%)。有人推荐进行两次EPDS测量加一次访谈,但尚未得到充分测试。

解读

筛查产后抑郁症可能是一项合适的措施。然而,对于爱丁堡方法及其他后续模式在挪威的疗效,以及阳性检测的截断点达成共识,还需要更多的了解。

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