Division of Pediatric Neurology, Primary Children's Hospital, The University of Utah, Salt Lake City, UT, USA.
Curr Infect Dis Rep. 2014 Mar;16(3):391. doi: 10.1007/s11908-014-0391-3.
West Nile virus, a flavivirus identified in Africa in the 1930s, appeared in the Western Hemisphere in 1999. Since its appearance, West Nile virus has caused nearly 40,000 cases of human disease in the US and more than 1,500 deaths, mostly among elderly persons with neuroinvasive disease. This review summarizes recent information regarding the clinical manifestations and prevention of West Nile virus infections in children, and emphasizes that although West Nile virus fever and neuroinvasive disease primarily affect adults, infants and children remain at risk of serious complications, including death, from this disorder.
西尼罗河病毒,一种于 20 世纪 30 年代在非洲发现的黄病毒,于 1999 年出现在西半球。自出现以来,西尼罗河病毒已在美国导致近 40000 例人类疾病和 1500 多人死亡,主要发生在患有神经侵袭性疾病的老年人中。这篇综述总结了有关儿童西尼罗河病毒感染的临床表现和预防的最新信息,并强调尽管西尼罗河病毒发热和神经侵袭性疾病主要影响成年人,但婴儿和儿童仍有患这种疾病的严重并发症的风险,包括死亡。