论呼吸分析中统计学的重要性——是希望还是诅咒？
On the importance of statistics in breath analysis--hope or curse?
机构信息
Division of Biostatistics, Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA.
出版信息
J Breath Res. 2014 Mar;8(1):012001. doi: 10.1088/1752-7155/8/1/012001. Epub 2014 Feb 24.
Abstract
As we saw at the 2013 Breath Analysis Summit, breath analysis is a rapidly evolving field. Increasingly sophisticated technology is producing huge amounts of complex data. A major barrier now faced by the breath research community is the analysis of these data. Emerging breath data require sophisticated, modern statistical methods to allow for a careful and robust deduction of real-world conclusions.
摘要
正如我们在 2013 年呼吸分析峰会上所见，呼吸分析是一个快速发展的领域。日益复杂的技术正在产生大量复杂的数据。目前，呼吸研究界面临的一个主要障碍是对这些数据的分析。新兴的呼吸数据需要复杂的现代统计方法，以便能够仔细而稳健地推断出实际结论。
相似文献
1
On the importance of statistics in breath analysis--hope or curse?
J Breath Res. 2014 Mar;8(1):012001. doi: 10.1088/1752-7155/8/1/012001. Epub 2014 Feb 24.
2
Comparison of fractional exhaled nitric oxide levels measured using the NIOX VERO and NOA 280i.
Ann Allergy Asthma Immunol. 2017 Oct;119(4):383-385. doi: 10.1016/j.anai.2017.07.026.
3
ATS Workshop Proceedings: Exhaled nitric oxide and nitric oxide oxidative metabolism in exhaled breath condensate: Executive summary.
Am J Respir Crit Care Med. 2006 Apr 1;173(7):811-3. doi: 10.1164/rccm.2601014.
4
[Exhaled breath condensates analysis].
Pol Arch Med Wewn. 2004 Aug;112(2):975-82.
5
Exhaled biomarkers.
Chest. 2006 Nov;130(5):1541-6. doi: 10.1378/chest.130.5.1541.
6
Effect of spirometry on exhaled nitric oxide values in asthmatic children.
Pediatr Allergy Immunol. 2019 Sep;30(6):654-657. doi: 10.1111/pai.13086. Epub 2019 Jul 15.
7
Between-occasion repeatability of fractional exhaled nitric oxide measurements in children.
J Bras Pneumol. 2018 Jan-Feb;44(1):52-54. doi: 10.1590/S1806-37562017000000127.
8
Transparent reporting of all GRADE criteria in clinical practice guidelines.
Am J Respir Crit Care Med. 2012 May 15;185(10):1129; author reply 1129-30. doi: 10.1164/ajrccm.185.10.1129.
9
Exhaled NO in asthma: still in touch or definitively out of bounds?
Allergy. 2010 Mar;65(3):281-2. doi: 10.1111/j.1398-9995.2009.02241.x. Epub 2009 Nov 2.
10
Current application of exhaled nitric oxide in clinical practice.
J Allergy Clin Immunol. 2016 Nov;138(5):1296-1298. doi: 10.1016/j.jaci.2016.09.002. Epub 2016 Sep 21.
引用本文的文献
1
Exhaled VOC detection in lung cancer screening: a comprehensive meta-analysis.
BMC Cancer. 2024 Jun 27;24(1):775. doi: 10.1186/s12885-024-12537-7.
2
Breath Collection from Children for Disease Biomarker Discovery.
J Vis Exp. 2019 Feb 14(144). doi: 10.3791/59217.
3
Exhaled volatile substances mirror clinical conditions in pediatric chronic kidney disease.
PLoS One. 2017 Jun 1;12(6):e0178745. doi: 10.1371/journal.pone.0178745. eCollection 2017.
4
Comparative Analysis of VOCs in Exhaled Breath of Amyotrophic Lateral Sclerosis and Cervical Spondylotic Myelopathy Patients.
Sci Rep. 2016 May 23;6:26120. doi: 10.1038/srep26120.
5
Carotta: Revealing Hidden Confounder Markers in Metabolic Breath Profiles.
Metabolites. 2015 Jun 10;5(2):344-63. doi: 10.3390/metabo5020344.
本文引用的文献
1
Puzzlingly High Correlations in fMRI Studies of Emotion, Personality, and Social Cognition.
Perspect Psychol Sci. 2009 May;4(3):274-90. doi: 10.1111/j.1745-6924.2009.01125.x.
2
Single high flow exhaled nitric oxide is an imperfect proxy for distal nitric oxide.
Occup Environ Med. 2013 Jul;70(7):519-20. doi: 10.1136/oemed-2013-101458. Epub 2013 May 5.
3
Integrated statistical learning of metabolic ion mobility spectrometry profiles for pulmonary disease identification.
Genet Mol Res. 2012 Aug 16;11(3):2733-44. doi: 10.4238/2012.July.10.17.
4
Data interpretation in breath biomarker research: pitfalls and directions.
J Breath Res. 2012 Sep;6(3):036007. doi: 10.1088/1752-7155/6/3/036007. Epub 2012 Aug 2.
5
Extended NO analysis in health and disease.
J Breath Res. 2012 Dec;6(4):047103. doi: 10.1088/1752-7155/6/4/047103. Epub 2012 Jun 7.
6
Breath biomarkers in environmental health science: exploring patterns in the human exposome.
J Breath Res. 2011 Dec;5(4):046005. doi: 10.1088/1752-7155/5/4/046005. Epub 2011 Sep 9.
7
A mathematical model for breath gas analysis of volatile organic compounds with special emphasis on acetone.
J Math Biol. 2011 Nov;63(5):959-99. doi: 10.1007/s00285-010-0398-9. Epub 2011 Jan 14.
8
Physiological modeling of isoprene dynamics in exhaled breath.
J Theor Biol. 2010 Dec 21;267(4):626-37. doi: 10.1016/j.jtbi.2010.09.028. Epub 2010 Sep 29.
9
Wilcoxon-Mann-Whitney or t-test? On assumptions for hypothesis tests and multiple interpretations of decision rules.
Stat Surv. 2010;4:1-39. doi: 10.1214/09-SS051.
10
Quantifying proximal and distal sources of NO in asthma using a multicompartment model.
J Appl Physiol (1985). 2010 Apr;108(4):821-9. doi: 10.1152/japplphysiol.00795.2009. Epub 2010 Jan 21.
Zotero 插件