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复杂医疗状况供体活体肾移植的结果:对供体和受体的影响

The Outcomes of Living Kidney Donation from Medically Complex Donors: Implications for the Donor and the Recipient.

作者信息

Niemi Matthew, Mandelbrot Didier A

机构信息

Division of Nephrology, Department of Medicine Beth Israel Deaconess Medical Center 185 Pilgrim Road, Farr 8 Boston, MA 02215

The Transplant Center Beth Israel Deaconess Medical Center 110 Francis Street, LMOB 7 Boston, MA 02215.

出版信息

Curr Transplant Rep. 2014 Mar 1;1(1):1-9. doi: 10.1007/s40472-013-0001-6.

Abstract

Living kidney donation is an important option for patients with end-stage renal disease (ESRD), and has improved life expectancy and quality for patients otherwise requiring maintenance dialysis or deceased-donor transplantation. Given the favorable outcomes of live donation and the shortage of organs to transplant, individuals with potentially unfavorable demographic and clinical characteristics are increasingly being permitted to donate kidneys. While this trend has successfully expanded the live donor pool, it has raised concerns as to which acceptance criteria are safe. This review aims to summarize the existing literature on the outcomes of transplantation from medically complex, living kidney donors, including both donor and recipient outcomes when available.

摘要

活体肾捐赠对于终末期肾病(ESRD)患者而言是一个重要选择,并且提高了那些原本需要维持性透析或接受 deceased 供体移植患者的预期寿命和生活质量。鉴于活体捐赠的良好效果以及可供移植器官的短缺,具有潜在不利人口统计学和临床特征的个体越来越多地被允许捐赠肾脏。虽然这一趋势成功地扩大了活体供体库,但人们对哪些接受标准是安全的产生了担忧。本综述旨在总结现有关于来自医学情况复杂的活体肾供体移植结果的文献,包括在可行时供体和受体的结果。

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