Vallböhmer D, Knoefel W T
Chirurgische Klinik (A), Heinrich-Heine-Universität und Universitätsklinikum Düsseldorf, Deutschland.
Zentralbl Chir. 2014 Feb;139(1):23-7. doi: 10.1055/s-0033-1360338. Epub 2014 Feb 28.
With the exception of tumours limited to the mucosa, surgical resection of the primary tumour and its local lymph node metastases still remains the sole option for a curative therapy for potentially resectable gastric cancer, as long as a complete tumour resection (R0 resection) can be performed. In this context, the extent of surgical radicality has been discussed over the last years, especially based on the following aspects: 1. extent of lymphadenectomy/need for splenectomy; 2. subtotal versus total gastrectomy; 3. surgical therapy for cardia cancer; 4. operative approach in cT4-tumours; 5. laparoscopic versus open surgery. Based on the recent study results as well as the current guidelines, this review will discuss these specific issues and gives an insight about the recommended surgical radicality in gastric cancer.
除局限于黏膜层的肿瘤外,只要能进行完整的肿瘤切除(R0切除),对潜在可切除的胃癌进行原发肿瘤及其局部淋巴结转移灶的手术切除仍是唯一的治愈性治疗选择。在这种情况下,过去几年一直在讨论手术根治的范围,特别是基于以下几个方面:1. 淋巴结清扫范围/是否需要脾切除;2. 次全胃切除术与全胃切除术;3. 贲门癌的手术治疗;4. cT4期肿瘤的手术方式;5. 腹腔镜手术与开放手术。基于最近的研究结果以及当前的指南,本综述将讨论这些具体问题,并深入探讨胃癌推荐的手术根治范围。