Jain Keerti, Mehra Neelesh Kumar, Jain Narendra Kumar
Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr. H. S. Gour Central University, Sagar, Madhya Pradesh 470003, India.
Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr. H. S. Gour Central University, Sagar, Madhya Pradesh 470003, India.
Curr Opin Pharmacol. 2014 Apr;15:97-106. doi: 10.1016/j.coph.2014.01.006. Epub 2014 Mar 2.
Nanopharmacology is a relatively newer branch of pharmacology which investigates interaction of a nanomedicine with living systems at the nanoscale level. Modern medicine is increasingly concerned with various surface modified nanocarriers, such as dendrimers, nanoparticles, carbon based nanomaterials, polymer-drug nanoconjugates, etc., which have immense therapeutic potential by target specific drug delivery, using nanoscaffolding and nanocontainers, owing to the specific physical, chemical and biological properties of these moieties that is related to their nanoscale size range. Nanopharmacology could have potential medical and pharmaceutical benefits via applications of nanotechnology in the delivery of therapeutic and diagnostic agents. Nanomaterials may be expected to find application in the cardiovascular, as well as, renal arena, in the near future.
纳米药理学是药理学中一个相对较新的分支,它研究纳米药物与纳米尺度下生物系统的相互作用。现代医学越来越关注各种表面修饰的纳米载体,如树枝状大分子、纳米颗粒、碳基纳米材料、聚合物-药物纳米共轭物等,由于这些部分的特定物理、化学和生物学特性与其纳米尺度范围相关,它们通过靶向特定药物递送、使用纳米支架和纳米容器具有巨大的治疗潜力。通过纳米技术在治疗和诊断剂递送中的应用,纳米药理学可能具有潜在的医学和药学益处。预计纳米材料在不久的将来可应用于心血管和肾脏领域。