Briend A, Legrand P, Bocquet A, Girardet J-P, Bresson J-L, Chouraqui J-P, Darmaun D, Dupont C, Frelut M L, Goulet O, Hankard R, Rieu D, Simeoni U, Turck D, Vidailhet M
Institut de recherche pour le développement, 44, boulevard de Dunkerque, 13002 Marseille, France.
Inra USC 2012, 35000 Rennes, France.
Arch Pediatr. 2014 Apr;21(4):424-38. doi: 10.1016/j.arcped.2013.12.026. Epub 2014 Mar 11.
Lipids are an important source of energy for young children and play a major role in the development and functioning of nervous tissue. Essential fatty acids and their long-chain derivatives also fulfill multiple metabolic functions and play a role in the regulation of numerous genes. The Food and Agriculture Organization of the United Nations (FAO), the World Health Organization (WHO), and the French Agency for Food, Environmental and Occupational Health & Safety (Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail [ANSES]) have recently recommended a minimum daily intake in preformed long-chain polyunsaturated fatty acids (LC-PUFAs): arachidonic acid (ARA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). Mother's milk remains the only reference, but the large variability in its DHA content does not guarantee that breastfed children receive an optimal DHA intake if the mother's intake is insufficient. For children fed with infant formulas, ARA and DHA intake is often below the recommended intake because only one-third of infant formulas available on the market in France are enriched in LC-PUFAs. For all children, linoleic acid (LA) intake is on average higher than the minimal recommended values. The consequences of these differences between intake and recommended values are uncertain. A cautious attitude is to come close to the current recommendations and to advise sufficient consumption of DHA in breastfeeding women. For bottle-fed children, infant formulas enriched in LC-PUFAs and with moderate levels of LA should be preferred. LC-PUFA-rich fish should be consumed during breastfeeding, and adapted vegetable oils when complementary foods are introduced.
脂质是幼儿重要的能量来源,在神经组织的发育和功能中发挥着主要作用。必需脂肪酸及其长链衍生物还具有多种代谢功能,并在众多基因的调控中发挥作用。联合国粮食及农业组织(FAO)、世界卫生组织(WHO)以及法国食品、环境与职业健康安全局(法国国家食品、环境及劳动卫生安全局[ANSES])最近建议了预先形成的长链多不饱和脂肪酸(LC-PUFA)的每日最低摄入量:花生四烯酸(ARA)、二十碳五烯酸(EPA)和二十二碳六烯酸(DHA)。母乳仍然是唯一的参考标准,但如果母亲的摄入量不足,母乳中DHA含量的巨大差异并不能保证母乳喂养的儿童获得最佳的DHA摄入量。对于食用婴儿配方奶粉的儿童,ARA和DHA的摄入量往往低于推荐摄入量,因为法国市场上只有三分之一的婴儿配方奶粉富含LC-PUFA。对于所有儿童来说,亚油酸(LA)的摄入量平均高于最低推荐值。摄入量与推荐值之间这些差异的后果尚不确定。谨慎的做法是接近当前的建议,并建议哺乳期妇女充分摄入DHA。对于人工喂养的儿童,应优先选择富含LC-PUFA且LA含量适中的婴儿配方奶粉。哺乳期应食用富含LC-PUFA的鱼类,引入辅食时应选择合适的植物油。