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伊朗沙漠地区克尔曼特应性皮炎的流行病学及临床特征

Epidemiology and clinical features of atopic dermatitis in kerman, a desert area of iran.

作者信息

Farajzadeh Saeedeh, Esfandiarpour Iraj, Sedaghatmanesh Maryam, Saviz Mahdieh

机构信息

Department of Pediatric Dermatology, Dermatology and Leishmania Research Center, Kerman University of Medical Sciences, Kerman, Iran.

出版信息

Ann Dermatol. 2014 Feb;26(1):26-34. doi: 10.5021/ad.2014.26.1.26. Epub 2014 Feb 17.

Abstract

BACKGROUND

Epidemiologic studies of atopic dermatitis (AD) in desert areas are still lacking.

OBJECTIVE

The aim of this study was to investigate the epidemiology of AD in children in Kerman city, a desert area in Iran.

METHODS

We evaluated preschool children (age, 2 to 7 years) and primary school students (age, greater than 7 up to 12 years) in Kerman. We selected 865 students to estimate the prevalence and assess other features of AD such as distribution of lesions, personal history, family history of atopy, aggravating factors, associated symptoms, and morphological variants.

RESULTS

The prevalence of AD was 9.1% in our study population. The prevalence of AD was 9.17% and 9.09% in males and females, respectively. The prevalence of AD in the age range of 2 to 7 years was 13.53% and 8.33% among children aged greater than 7 up to 12 years. In total, 82.27% of the patients were in chronic stage of the disease, and 31.6% had a personal history of other atopic diseases. At least one first-degree family member with atopy was seen in 46.83% of the patients. The most common sites of involvement were the head and neck. The most involved areas in the limbs were extensor surfaces. The most frequent morphological variant of AD was the common type.

CONCLUSION

The prevalence of AD in Kerman was higher than in other Iranian cities but lower than that in developed countries. Diversity in the clinical features of AD has been observed among different studies, and the diagnostic criteria of AD should be adapted in proportion to the studied area.

摘要

背景

沙漠地区特应性皮炎(AD)的流行病学研究仍然缺乏。

目的

本研究旨在调查伊朗沙漠地区克尔曼市儿童AD的流行病学情况。

方法

我们对克尔曼市的学龄前儿童(年龄2至7岁)和小学生(年龄大于7岁至12岁)进行了评估。我们选取了865名学生以估计患病率并评估AD的其他特征,如皮损分布、个人史、特应性家族史、加重因素、相关症状及形态学变异。

结果

在我们的研究人群中,AD的患病率为9.1%。男性和女性的AD患病率分别为9.17%和9.09%。2至7岁年龄组的AD患病率为13.53%,大于7岁至12岁儿童中的患病率为8.33%。总体而言,82.27%的患者处于疾病的慢性期,31.6%有其他特应性疾病的个人史。46.83%的患者至少有一位患有特应性疾病的一级家庭成员。最常受累的部位是头颈部。四肢最常受累的部位是伸侧表面。AD最常见的形态学变异类型是常见型。

结论

克尔曼市AD的患病率高于伊朗其他城市,但低于发达国家。不同研究中观察到AD临床特征存在差异,AD的诊断标准应根据研究地区进行适当调整。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d304/3956792/ea93bf69cecb/ad-26-26-g001.jpg

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