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[慢性硬膜下血肿钻孔引流术后床头位置:随机对照试验的系统评价和荟萃分析]

[Postoperative bed header position after burr-hole drainage of chronic subdural haematoma: systematic review and meta-analysis of randomised controlled trials].

作者信息

Alcalá-Cerra Gabriel, Moscote-Salazar Luis Rafael, Paternina-Caicedo Ángel, Gutiérrez-Paternina Juan José, Niño-Hernández Lucía M, Sabogal-Barrios Rubén

机构信息

Grupo de Investigación en Ciencias Neurológicas y Neurociencias (CISNEURO), Cartagena de Indias, Colombia; Departamento de Neurocirugía, Universidad de Cartagena, Cartagena de Indias, Colombia.

Grupo de Investigación en Ciencias Neurológicas y Neurociencias (CISNEURO), Cartagena de Indias, Colombia.

出版信息

Neurocirugia (Astur). 2014 May-Jun;25(3):99-107. doi: 10.1016/j.neucir.2013.11.002. Epub 2014 Mar 20.

Abstract

INTRODUCTION

Several studies have suggested the possible influence of postoperative bed header position on the risk of symptomatic recurrences and medical complications in patients who have been intervened due chronic subdural haematomas. Nevertheless, this hypothesis has not been assessed by a meta-analysis.

METHODS

All randomised controlled trials analysing symptomatic recurrence rates in patients who underwent burr-hole drainage of chronic subdural haematomas, describing postoperative bed header positioning, were included. The primary outcome was risk of recurrence and the secondary outcome were the risks of reoperation and medical complications. Results were presented as pooled relative risks, with 95% confidence intervals.

RESULTS

A total of 4 controlled studies were included. Pooled relative risks were: symptomatic recurrences 0.51 ([95% CI: 0.22-1.16]; P=.11), reoperations, 1.07 ([95% CI: 0.42-2.69]; P=.89) and medical complications, 1.15 ([95% CI: 0.7-1.91]; P=.58). No statistically significant heterogeneity was found in any of the analyses.

CONCLUSION

There were no differences regarding frequency of symptomatic recurrences, reoperations or medical complications in patients who were maintained in a flat position compared with those whose bed header was elevated during the postoperative course. Despite there being consistency between the results, there is a potential risk of bias; thus proscribing definitive recommendations until studies with higher methodological quality are available.

摘要

引言

多项研究表明,术后床头位置可能会对因慢性硬膜下血肿接受干预治疗的患者出现症状复发及医疗并发症的风险产生影响。然而,这一假设尚未通过荟萃分析进行评估。

方法

纳入所有分析慢性硬膜下血肿钻孔引流患者症状复发率并描述术后床头位置的随机对照试验。主要结局为复发风险,次要结局为再次手术风险和医疗并发症风险。结果以合并相对风险及95%置信区间表示。

结果

共纳入4项对照研究。合并相对风险分别为:症状复发0.51([95%置信区间:0.22 - 1.16];P = 0.11),再次手术1.07([95%置信区间:0.42 - 2.69];P = 0.89),医疗并发症1.15([95%置信区间:0.7 - 1.91];P = 0.58)。在任何分析中均未发现具有统计学意义的异质性。

结论

与术后床头抬高的患者相比,术后保持平卧位的患者在症状复发、再次手术或医疗并发症的发生率方面并无差异。尽管结果具有一致性,但存在潜在的偏倚风险;因此,在有更高方法学质量的研究出现之前,暂不给出明确建议。

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