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社会经济地位和农村地区对冠状动脉旁路移植术后早期结局和中期生存的影响:来自多中心注册研究的见解

Impact of socioeconomic status and rurality on early outcomes and mid-term survival after CABG: insights from a multicentre registry.

作者信息

Shi William Y, Yap Cheng-Hon, Newcomb Andrew E, Hayward Philip A, Tran Lavinia, Reid Christopher M, Smith Julian A

机构信息

Department of Cardiothoracic Surgery, St Vincent's Hospital Melbourne, Australia.

Department of Cardiothoracic Surgery, Geelong Hospital, Australia; Department of Epidemiology and Preventive Medicine, Monash University, Australia.

出版信息

Heart Lung Circ. 2014 Aug;23(8):726-36. doi: 10.1016/j.hlc.2014.02.008. Epub 2014 Feb 28.

Abstract

BACKGROUND

We examined whether socioeconomic status and rurality influenced outcomes after coronary surgery.

METHODS

We identified 14,150 patients undergoing isolated coronary surgery. Socioeconomic and rurality data was obtained from the Australian Bureau of Statistics and linked to patients' postcodes. Outcomes were compared between categories of socioeconomic disadvantage (highest versus lowest quintiles, n= 3150 vs. 2469) and rurality (major cities vs. remote, n=9598 vs. 839).

RESULTS

Patients from socioeconomically-disadvantaged areas experienced a greater burden of cardiovascular risk factors including diabetes, obesity and current smoking. Thirty-day mortality (disadvantaged 1.6% vs. advantaged 1.6%, p>0.99) was similar between groups as was late survival (7 years: 83±0.9% vs. 84±1.0%, p=0.79). Those from major cities were less likely to undergo urgent surgery. There was similar 30-day mortality (major cities: 1.6% vs. remote: 1.5%, p=0.89). Patients from major cities experienced improved survival at seven years (84±0.5% vs. 79±2.0%, p=0.010). Propensity-analysis did not show socioeconomic status or rurality to be associated with late outcomes.

CONCLUSION

Patients presenting for coronary artery surgery from different socioeconomic and geographic backgrounds exhibit differences in their clinical profile. Patients from more rural and remote areas appear to experience poorer long-term survival, though this may be partially driven by the population's clinical profile.

摘要

背景

我们研究了社会经济地位和农村地区情况是否会影响冠状动脉手术后的结果。

方法

我们确定了14150例接受单纯冠状动脉手术的患者。社会经济和农村地区数据来自澳大利亚统计局,并与患者的邮政编码相关联。比较了社会经济劣势类别(最高五分位数与最低五分位数,n = 3150对2469)和农村地区情况(大城市与偏远地区,n = 9598对839)之间的结果。

结果

来自社会经济劣势地区的患者经历了更大的心血管危险因素负担,包括糖尿病、肥胖和当前吸烟。两组之间的30天死亡率(劣势组1.6%对优势组1.6%,p>0.99)相似,晚期生存率也相似(7年:83±0.9%对84±1.0%,p = 0.79)。来自大城市的患者接受急诊手术的可能性较小。30天死亡率相似(大城市:1.6%对偏远地区:1.5%,p = 0.89)。来自大城市的患者在7年时生存率有所提高(84±0.5%对79±2.0%,p = 0.010)。倾向分析未显示社会经济地位或农村地区情况与晚期结果相关。

结论

来自不同社会经济和地理背景的接受冠状动脉手术的患者在临床特征上存在差异。来自农村和偏远地区的患者似乎长期生存率较差,尽管这可能部分是由人群的临床特征所驱动。

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