van den Broek A H, Lida J
Department of Veterinary Clinical Studies, Royal (Dick) School of Veternary Studies, Summerhall, Edinburgh.
Res Vet Sci. 1989 Jan;46(1):100-4.
The serum protein concentrations of dogs with confirmed spontaneous hyperadrenocorticalism were determined by agarose gel electrophoresis before and during treatment with mitotane. In untreated animals a significant increase was detected in the mean concentration of total protein and the mean concentration and percentage of alpha-2 globulin. The mean concentration and percentage of albumin and gamma-globulin were significantly decreased. In animals on treatment the mean concentration of total proteins and the mean concentration and percentage of beta-2 globulin were significantly reduced.
对确诊为自发性肾上腺皮质功能亢进的犬,在使用米托坦治疗前及治疗期间,通过琼脂糖凝胶电泳测定其血清蛋白浓度。在未经治疗的动物中,总蛋白平均浓度、α-2球蛋白平均浓度及百分比显著升高。白蛋白和γ-球蛋白的平均浓度及百分比显著降低。在接受治疗的动物中,总蛋白平均浓度、β-2球蛋白平均浓度及百分比显著降低。