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[接受回肠代膀胱术作为尿流改道形式的患者术后肾功能恶化程度与输尿管插入类型的关系]

[Degree of postoperative renal deterioration in patients who have undergone ileal conduit as a form of urinary diversion in relation to the type of insertion of the ureter].

作者信息

Kajmaković B M, Dzamić Z M, Pejcić T, Milković B, Aćimović M, Djokić J Hadzi

出版信息

Acta Chir Iugosl. 2013;60(3):17-24. doi: 10.2298/aci1303017k.

Abstract

UNLABELLED

Substitution of the bladder with segment of the digestive tract, within the radical treatment of bladder cancer, as well as treatment of the other bladder abnormality, is extremely demanding surgical procedure, that aims adequate treatment of the underlying disease and provide patient's renal function within physiological level. Surgical implantation of the ureter into the intestinal segment are an important part of the surgical technique, the formation of ileal conduit, with the ultimate aim of providing a more natural way of evacuation of urine from the upper urinary tract in terms of maintaining the adequate quality of renal function. Which of the existing surgical method of implantation of ureter in the intestinal segment will be applied, it is for urologist to decided, according to his affinity and/or his operating school of origin. The literature describes many procedures of this technique (Wallace A, B Wallace, Nesbit-Bricker, Le Duc). Bearing in mind that the ileal conduit, as a form of supravesical derivation, is still one of most widely used method of urinary diversion, with a very large number of patients during the follow-up period were recorded certain complications of renal function disorders, which by some authors attributed to a type of ureterointestinal anastomoses, during the creation of ileal conduit. Having in mind the fact of unnatural route of elimination of urine from the upper urinary tract that occurs during creation of ileal conduit, it is reasonable to expect some degree of renal deterioration. These complications require prompt resolution. Bearing in mind the fact of unnatural route of elimination of urine from the upper urinary tract that occurs during creation of ileal conduit, it is reasonable to expect that the renal function over the time will start to show signs of incipient or advanced failure.

OBJECTIVE

The main objective is to show the degree of renal deterioration, postoperatively, according to the type of insertion of the ureters to the ileal conduit.

METHODS AND PATIENTS

The study was conducted retrospectively on material of Urological Clinic, Clinical Center of Serbia and on material of Faculty of Medicine, University of Belgrade, on 193 patients, for a period of five years (2007 to 2011), with a time of postoperative follow-up of patients up to 48 months (four years). Assessment of the level of renal deteriorisation was performed by ultrasound examination during regular audits of patients during follow-up.

CONCLUSION

It was found that all three examed techniques in an insertion of ureter into ileal conduit were equally satisfactorily, with the similar degree of postoperative complications. Based on these facts, we can conclude, that the quality of life of patients in all three analyzed groups of ureteral insertion in the ileal conduit, approximately the same.

摘要

未标注

在膀胱癌根治性治疗以及其他膀胱异常疾病的治疗中,用消化道节段替代膀胱是一项极具挑战性的外科手术,其目的是充分治疗潜在疾病并使患者的肾功能维持在生理水平。将输尿管外科植入肠段是手术技术的重要组成部分,即回肠代膀胱术的形成,其最终目的是在维持足够肾功能质量的前提下,提供一种更自然的上尿路尿液引流方式。采用哪种现有的输尿管植入肠段的手术方法,由泌尿科医生根据其偏好和/或其所属的手术流派来决定。文献中描述了该技术的许多操作方法(华莱士A式、华莱士B式、内斯比特-布里克式、勒迪克式)。鉴于回肠代膀胱术作为一种膀胱上引流方式,仍然是最广泛使用的尿液改道方法之一,在大量患者的随访期间记录到了一些肾功能障碍并发症,一些作者将其归因于回肠代膀胱术创建过程中的某种输尿管肠吻合类型。考虑到回肠代膀胱术创建过程中上尿路尿液排出路径不自然这一事实,预计肾功能会出现一定程度的恶化。这些并发症需要及时解决。考虑到回肠代膀胱术创建过程中上尿路尿液排出路径不自然这一事实,合理的预期是随着时间推移肾功能将开始出现早期或晚期衰竭的迹象。

目的

主要目的是根据输尿管插入回肠代膀胱的类型,展示术后肾功能恶化的程度。

方法与患者

本研究对塞尔维亚临床中心泌尿外科诊所的资料以及贝尔格莱德大学医学院的资料进行了回顾性研究,研究对象为193例患者,为期五年(2007年至2011年),患者术后随访时间长达48个月(四年)。在随访期间定期对患者进行超声检查,评估肾功能恶化程度。

结论

发现输尿管插入回肠代膀胱的所有三种检查技术同样令人满意,术后并发症程度相似。基于这些事实,我们可以得出结论,回肠代膀胱术中输尿管插入的所有三个分析组患者的生活质量大致相同。

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