中国患者原发性肾上腺脂肪瘤性肿瘤的诊断与治疗：一项31年的随访研究。
The diagnosis and treatment of primary adrenal lipomatous tumours in Chinese patients: A 31-year follow-up study.
作者信息
Zhao Juping, Sun Fukang, Jing Xiaolong, Zhou Wenlong, Huang Xin, Wang Haofei, Zhu Yu, Yuan Fei, Shen Zhoujun
机构信息
Department of Urology, Ruijin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China;
Department of Pathology, Ruijin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China Juping Zhao and Xin Huang contributed equally to this work.
出版信息
Can Urol Assoc J. 2014 Mar-Apr;8(3-4):E132-6. doi: 10.5489/cuaj.977.
INTRODUCTION
Adrenal lipomatous tumours (ALTs) are rarely encountered in clinical practice and consequently little is known about their clinical features.
METHODS
We analyze the clinical features, diagnosis and treatment of ALTs based on cases presenting at a single centre over a 31-year period. We reviewed clinical data from patients with primary adrenal tumours treated at the Ruijin Hospital, Shanghai between January 1980 and December 2010.
RESULTS
A total of 73 cases of primary ALTs in 22 men and 51 women (mean age 51.1±14.2 years) were reviewed. The ALTs included 65 myelolipomas (89.0%), 3 lipomas (4.1%), 2 angiomyolipomas (2.7%), 2 teratomas (2.7%), and 1 liposarcoma (1.4%). Of the total 73 patients, 24 of them had tumours in the left adrenal gland, 47 in the right gland and 2 had bilateral tumours. In total, 51 patients underwent open surgery and 22 laparoscopic surgery.
CONCLUSION
Myelolipoma is predominant among the various types of lipomatous adrenal gland tumours; it accounts for about 90% of all cases. Surgery is recommended for tumours ≥3.5 cm in diameter, for all cases of symptomatic tumour, and for cases of teratoma or liposarcoma identified by preoperative imaging.
引言
肾上腺脂肪瘤性肿瘤（ALTs）在临床实践中很少见，因此对其临床特征了解甚少。
方法
我们基于一个中心31年间收治的病例分析ALTs的临床特征、诊断和治疗。我们回顾了1980年1月至2010年12月在上海瑞金医院接受治疗的原发性肾上腺肿瘤患者的临床资料。
结果
共回顾了73例原发性ALTs病例，其中男性22例，女性51例（平均年龄51.1±14.2岁）。这些ALTs包括65例髓脂肪瘤（89.0%）、3例脂肪瘤（4.1%）、2例血管平滑肌脂肪瘤（2.7%）、2例畸胎瘤（2.7%）和1例脂肪肉瘤（1.4%）。在73例患者中，24例肿瘤位于左肾上腺，47例位于右肾上腺，2例为双侧肿瘤。共有51例患者接受了开放手术，22例接受了腹腔镜手术。
结论
髓脂肪瘤在各种肾上腺脂肪瘤性肿瘤中占主导地位；约占所有病例的90%。对于直径≥3.5 cm的肿瘤、所有有症状的肿瘤病例以及术前影像学检查发现的畸胎瘤或脂肪肉瘤病例，建议进行手术治疗。
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