Costandi Shrif, Chopko Bohdan, Mekhail Mena, Dews Teresa, Mekhail Nagy
Department of Pain Management, Cleveland Clinic, Cleveland, Ohio, U.S.A.
Pain Pract. 2015 Jan;15(1):68-81. doi: 10.1111/papr.12188. Epub 2014 Apr 12.
Lumbar spinal stenosis (LSS) functionally impacts significant numbers of Americans per year. Current estimates place the number of Americans suffering from senescent lumbar spinal stenosis at 400,000. The prevalence of this disorder in patients ranging from 60 to 69 years of age is very high. Forty-seven percent of this age group have mild to moderate stenosis, and 19.7% have severe stenosis. As the baby boomer generation gets older, 10,000 individuals attain the age of 65 years every day in United States. LSS is becoming very common and will be a major healthcare issue as the population ages. Although LSS is not life threatening, it can cause substantial disability with limitations to performing daily activities, and thus, the associated negative impact on quality of life (QOL). This article reviews the pathophysiology and current treatment options for LSS, focusing on evidence-based treatment options.
腰椎管狭窄症(LSS)每年对大量美国人的功能产生影响。目前估计,患有衰老性腰椎管狭窄症的美国人数量为40万。这种疾病在60至69岁患者中的患病率非常高。这个年龄组中47%的人有轻度至中度狭窄,19.7%的人有重度狭窄。随着婴儿潮一代年龄的增长,美国每天有1万人年满65岁。LSS正变得非常普遍,随着人口老龄化,它将成为一个主要的医疗保健问题。虽然LSS不会危及生命,但它会导致严重残疾,限制日常活动的进行,因此,会对生活质量(QOL)产生相关的负面影响。本文综述了LSS的病理生理学和当前的治疗选择,重点关注基于证据的治疗选择。