Bigornia Sherman J, LaValley Michael P, Moore Lynn L, Northstone Kate, Emmett Pauline, Ness Andy R, Newby P K
Department of Pediatrics.
Biostatistics and.
J Nutr. 2014 Jul;144(7):1081-90. doi: 10.3945/jn.113.183640. Epub 2014 Apr 17.
Evidence of an association between milk intake and childhood adiposity remains inconsistent, with few data available regarding the effects of the amount of dairy fat consumed. This study examined the relation between dairy consumption (total, full, and reduced fat) at age 10 y on risk of excess adiposity at age 13 y in participants of the Avon Longitudinal Study of Parents and Children (ALSPAC; n = 2455). Intakes were assessed by 3-d dietary records. Total body fat mass (TBFM) using dual-energy X-ray absorptiometry was examined at 13 y. Outcomes included excess TBFM (top quintile of TBFM), overweight, and change in body mass index (BMI). The highest vs. lowest quartile of total dairy consumers (g/d) at age 10 y did not have an increased risk of excess TBFM (OR: 0.73; 95% CI: 0.46, 1.16; P-trend = 0.28) or overweight (OR: 0.69; 95% CI: 0.41, 1.15; P = 0.24) at age 13 y. Children in the highest quartile of full-fat dairy intakes vs. those in the lowest quartile had a reduced risk of excess TBFM (OR: 0.64; 95% CI: 0.41, 1.00; P = 0.04) and a suggestion of a reduction in overweight (OR: 0.65; 95% CI: 0.40, 1.06; P = 0.19) at age 13 y. Furthermore, the highest vs. lowest consumers of full-fat products had smaller gains in BMI during follow-up [2.5 kg/m² (95% CI: 2.2, 2.7) vs. 2.8 kg/m² (95% CI: 2.5, 3.0); P < 0.01]. Associations with reduced-fat dairy consumption did not attain statistical significance. In this study, dairy consumption was not related to excess fat accumulation during late childhood. Estimates had wide confidence limits but generally showed inverse relations between dairy intakes and risk of excess adiposity. Additional prospective research is warranted to confirm the effects of dairy intake on obesity in children.
牛奶摄入量与儿童肥胖之间的关联证据仍不一致,关于食用乳脂肪量的影响的数据很少。本研究在阿冯父母与儿童纵向研究(ALSPAC;n = 2455)的参与者中,调查了10岁时乳制品摄入量(全脂、低脂和脱脂)与13岁时肥胖风险之间的关系。摄入量通过3天饮食记录进行评估。13岁时使用双能X线吸收法检测全身脂肪量(TBFM)。结果包括过量TBFM(TBFM最高五分位数)、超重和体重指数(BMI)变化。10岁时全脂乳制品消费者最高四分位数与最低四分位数相比,13岁时过量TBFM风险没有增加(OR:0.73;95%CI:0.46,1.16;P趋势=0.28)或超重风险没有增加(OR:0.69;95%CI:0.41,1.15;P = 0.24)。全脂乳制品摄入量最高四分位数的儿童与最低四分位数的儿童相比,13岁时过量TBFM风险降低(OR:0.64;95%CI:0.41,1.00;P = 0.04),超重风险有降低趋势(OR:0.65;95%CI:0.40,1.06;P = 0.19)。此外,全脂产品最高消费者与最低消费者在随访期间BMI增加幅度较小[2.5kg/m²(95%CI:2.2,2.7)对2.8kg/m²(95%CI:2.5,3.0);P < 0.01]。与低脂乳制品消费的关联未达到统计学显著性。在本研究中,乳制品消费与儿童晚期脂肪过度积累无关。估计值的置信区间较宽,但总体显示乳制品摄入量与肥胖风险之间呈负相关。需要更多的前瞻性研究来证实乳制品摄入对儿童肥胖的影响。