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腹侧和背侧颊黏膜移植 1 期修复复杂前尿道狭窄。

Ventral and dorsal buccal grafting for 1-stage repair of complex anterior urethral strictures.

机构信息

Department of Urology, University of California, Irvine, Orange, CA.

Department of Urology, University of California, Irvine, Orange, CA.

出版信息

Urology. 2014 Jun;83(6):1418-22. doi: 10.1016/j.urology.2014.01.024. Epub 2014 Apr 16.

Abstract

OBJECTIVE

To describe our 14-year experience with a 1-stage tissue transfer urethroplasty technique.

METHODS

Eighteen patients underwent reconstruction with circumferential buccal grafting. All patients had anterior urethral strictures that included segments of total or near-total obliteration not amenable to excisional or augmented anastomotic repair and intact corpus spongiosum that could serve as a graft recipient bed. The mobilized corpus spongiosum was incised dorsally without transection, thereby preserving the continuity of the blood supply within the spongy tissue. Buccal mucosa was quilted to the corporal bodies to reconstruct the dorsal aspect of the urethra. Where there was obliterative or near-obliterative stricture disease, additional buccal mucosa was quilted to the dorsally incised, nontransected corpus spongiosum in continuity with the distally and proximally spatulated urethra. The repair was then completed by approximating dorsal and ventral buccal mucosal graft segments.

RESULTS

Follow-up included voiding cystourethrogram at 3 weeks, cystoscopy 4 months after surgery (1 patient refused), and subsequent follow-up. There was 1 early stricture recurrence, which was successfully treated with direct vision internal urethrotomy (success 94%, and 100% after 1 urethrotomy). Every patient was contacted and assessed at the time of manuscript preparation. All patients are currently free of obstructive symptoms attributed to stricture disease with a mean follow-up of 50 months (range, 5-171 months).

CONCLUSION

Dorsal and ventral buccal grafting appears to be an excellent option for a 1-stage repair of long obliterative anterior urethral strictures and strictures that include segments of obliterative or near-obliterative disease in selected cases.

摘要

目的

描述我们采用 1 期组织移植尿道成形术技术的 14 年经验。

方法

18 例患者接受了环状颊黏膜移植重建。所有患者均有前尿道狭窄,包括无法通过切除或增强吻合修复的完全或近乎完全闭塞段,以及完整的海绵体,可以作为移植物受体床。游离的海绵体在背侧切开而不横断,从而保持海绵组织内的血液供应连续性。颊黏膜被缝合到阴茎体上,以重建尿道的背侧。在存在闭塞性或近乎闭塞性狭窄病变的部位,额外的颊黏膜被缝合到背侧切开、未横断的海绵体上,与远端和近端切开的尿道连续。然后通过使背侧和腹侧颊黏膜移植物段接近来完成修复。

结果

随访包括术后 3 周的排尿性膀胱尿道造影、术后 4 个月的膀胱镜检查(1 例患者拒绝)以及随后的随访。有 1 例早期狭窄复发,通过直接视线下尿道内切开术成功治疗(成功率为 94%,1 次尿道内切开术后成功率为 100%)。在撰写手稿时,所有患者均已联系并评估。所有患者目前均无因狭窄疾病引起的阻塞症状,平均随访时间为 50 个月(范围 5-171 个月)。

结论

对于长段闭塞性前尿道狭窄和特定病例中包括闭塞性或近乎闭塞性病变段的狭窄,背侧和腹侧颊黏膜移植似乎是 1 期修复的绝佳选择。

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