Oláh Attila
Petz Aladár Megyei Oktató Kórház Sebészeti Osztály 9024 Győr Vasvári Pál út 2.
Magy Seb. 2014 Apr;67(2):39-43. doi: 10.1556/MaSeb.67.2014.2.1.
Intraductal papillary mucinous neoplasms (IPMN) have a distinguished role amongst the exocrine pancreatic tumours. Although IPMN is less than 1% of all pancreatic neoplasms, cystic tumours, which has got in the spotlight recently, belong to this histopathological subtype up to 20% to 30%. IPMN originate from the main- and accessory pancreatic ducts. Rate of malignancy, prognosis and, therefore, the operative indications can be quite different. Although the prognosis of ductal carcinoma developed on the basis of IPMN is similar to classic adenocarcinoma - 10% 5-year survival - the overall prognosis of IPMN is much more favourable with over 70% survival rate in case of non-invasive cancers. Hence, it is important the timely diagnosis and surgical resection of IPMN to prevent development of invasive cancer.
导管内乳头状黏液性肿瘤(IPMN)在外分泌性胰腺肿瘤中具有独特地位。尽管IPMN在所有胰腺肿瘤中占比不到1%,但近期备受关注的囊性肿瘤中,高达20%至30%属于这种组织病理学亚型。IPMN起源于主胰管和副胰管。其恶性率、预后以及手术指征可能有很大差异。尽管基于IPMN发展而来的导管癌预后与经典腺癌相似——5年生存率为10%,但IPMN的总体预后要好得多,非侵袭性癌症的生存率超过70%。因此,及时诊断和手术切除IPMN对于预防侵袭性癌症的发生很重要。