Webb Charles W, Webb Sandra M
Keauhou Urgent Care Center, 78-6831 Alii Dr., Suite 418, Kailua Kona, HI 96740.
Hawaii J Med Public Health. 2014 Apr;73(4):109-11.
Clinical research regarding the therapeutic benefits of cannabis ("marijuana") has been almost non-existent in the United States since cannabis was given Schedule I status in the Controlled Substances Act of 1970. In order to discover the benefits and adverse effects perceived by medical cannabis patients, especially with regards to chronic pain, we hand-delivered surveys to one hundred consecutive patients who were returning for yearly re-certification for medical cannabis use in Hawai'i. The response rate was 94%. Mean and median ages were 49.3 and 51 years respectively. Ninety-seven per cent of respondents used cannabis primarily for chronic pain. Average pain improvement on a 0-10 pain scale was 5.0 (from 7.8 to 2.8), which translates to a 64% relative decrease in average pain. Half of all respondents also noted relief from stress/anxiety, and nearly half (45%) reported relief from insomnia. Most patients (71%) reported no adverse effects, while 6% reported a cough or throat irritation and 5% feared arrest even though medical cannabis is legal in Hawai'i. No serious adverse effects were reported. These results suggest that Cannabis is an extremely safe and effective medication for many chronic pain patients. Cannabis appears to alleviate pain, insomnia, and may be helpful in relieving anxiety. Cannabis has shown extreme promise in the treatment of numerous medical problems and deserves to be released from the current Schedule I federal prohibition against research and prescription.
自1970年《管制物质法》将大麻(“ marijuana”)列为一类管制药物以来,美国几乎不存在关于大麻治疗益处的临床研究。为了了解医用大麻患者所感受到的益处和不良反应,特别是在慢性疼痛方面,我们亲自向一百名连续返回夏威夷进行医用大麻年度重新认证的患者发放了调查问卷。回复率为94%。平均年龄和年龄中位数分别为49.3岁和51岁。97%的受访者主要将大麻用于治疗慢性疼痛。在0至10分的疼痛量表上,疼痛平均改善了5.0(从7.8降至2.8),这意味着平均疼痛相对减轻了64%。所有受访者中有一半还表示压力/焦虑得到缓解,近一半(45%)报告失眠得到缓解。大多数患者(71%)报告无不良反应,而6%报告有咳嗽或喉咙刺激症状,5%表示尽管医用大麻在夏威夷是合法的,但仍担心会被逮捕。未报告有严重不良反应。这些结果表明,对于许多慢性疼痛患者来说,大麻是一种极其安全有效的药物。大麻似乎可以缓解疼痛、失眠,可能还有助于缓解焦虑。大麻在治疗众多医疗问题方面显示出了极大的前景,理应从目前联邦对其研究和处方的一类管制禁令中解禁。