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基于人群的研究:社会经济因素和种族对35535例住院异位妊娠管理及结局的影响

Population-based study on the effect of socioeconomic factors and race on management and outcomes of 35,535 inpatient ectopic pregnancies.

作者信息

Papillon-Smith Jessica, Imam Basel, Patenaude Valerie, Abenhaim Haim Arie

机构信息

Department of Obstetrics and Gynecology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.

University of Arizona College of Medicine, Phoenix, Arizona.

出版信息

J Minim Invasive Gynecol. 2014 Sep-Oct;21(5):914-20. doi: 10.1016/j.jmig.2014.04.005. Epub 2014 Apr 24.

Abstract

STUDY OBJECTIVE

To evaluate whether socioeconomic variables influence the management and outcomes of ectopic pregnancies.

DESIGN

Retrospective cohort study (Canadian Task Force classification II-2).

SETTING

Hospitals in the United States participating in the Health Care Cost and Utilization Project.

PATIENTS

Women (n = 35 535) with a primary discharge diagnosis of ectopic pregnancy.

INTERVENTIONS

Effect of socioeconomic factors and race/ethnicity on management and adverse outcomes of ectopic pregnancy.

MEASUREMENTS AND MAIN RESULTS

During the 9-year study, 35 535 ectopic pregnancies were identified. The development of hemoperitoneum in 8706 patients (24.50%) was the most common complication. Asian race was the sociodemographic variable most predictive of hemoperitoneum (odds ratio [OR], 1.41; 95% confidence interval [CI], 1.24-1.61; p < .01) and transfusion (OR, 1.62; 95% CI, 1.39-1.89; p < .01), and Medicare status was most influential on prolonged hospitalization (OR, 1.83; 95% CI, 1.36-2.47; p < .01). Major complications were not affected by socioeconomic factors. Laparotomy in 25 075 patients (70.6%) was the most common treatment option. Patients of Asian or Pacific Islander descent were least likely to be treated non-surgically (OR, 0.62; 95% CI, 0.51-0.76; p < .01), whereas Medicare recipients were most likely to be treated non-surgically (OR, 1.70; 95% CI, 1.32-2.18; p < .01). All non-white groups were less likely to undergo a laparoscopic approach.

CONCLUSION

Major complications from ectopic pregnancy are not influenced by socioeconomic variables; however, less serious complications and management approaches are persistently affected.

摘要

研究目的

评估社会经济变量是否会影响异位妊娠的治疗及结局。

设计

回顾性队列研究(加拿大工作组分类II-2)。

地点

参与医疗成本与利用项目的美国医院。

患者

以异位妊娠为主要出院诊断的女性(n = 35535)。

干预措施

社会经济因素及种族/民族对异位妊娠治疗及不良结局的影响。

测量指标及主要结果

在为期9年的研究中,共识别出35535例异位妊娠。8706例患者(24.50%)出现腹腔积血是最常见的并发症。亚洲种族是腹腔积血(优势比[OR],1.41;95%置信区间[CI],1.24 - 1.61;p <.01)和输血(OR,1.62;95% CI,1.39 - 1.89;p <.01)最具预测性的社会人口统计学变量,而医疗保险状态对住院时间延长影响最大(OR,1.83;95% CI,1.36 - 2.47;p <.01)。主要并发症不受社会经济因素影响。25075例患者(70.6%)接受剖腹手术是最常见的治疗选择。亚裔或太平洋岛民后裔患者接受非手术治疗的可能性最小(OR,0.62;95% CI,0.51 - 0.76;p <.01),而医疗保险受益患者接受非手术治疗的可能性最大(OR,1.70;95% CI,1.32 - 2.18;p <.01)。所有非白人组接受腹腔镜手术的可能性较小。

结论

异位妊娠的主要并发症不受社会经济变量影响;然而,不太严重的并发症及治疗方法持续受到影响。

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