兔体内使用或不使用阔筋膜张肌包裹的切碎软骨的结果比较。
Comparison of outcomes using diced cartilage with or without tensor fascia latae wrapping in rabbits.
作者信息
Hafezi Farhad, Abbaszadeh Abolfazl, Naghibzadeh Bijan, Ashtiani Abbas Kazemi, Fatemi Mohamad Javad, Nouhi Amir Hossein
机构信息
Dr Hafezi is Professor of Plastic Surgery, Iran University of Medical Sciences, St Fatima Hospital, and Burn Research Center, Tehran, IranDr Abbaszadeh is a plastic surgery fellow, Iran University of Medical Sciences, St Fatima Hospital, and Burn Research Center, Tehran, IranDrs Ashtiani and Fatemi are Associate Professors of Plastic Surgery at the Iran University of Medical Sciences, St Fatima Hospital, and Burn Research Center, Tehran, IranDr Naghibzadeh is Professor of Ear, Nose, and Throat Surgery at Shahid Beheshty University of Medical Sciences, Loghman Hakim Hospital, Tehran, IranDr Nouhi is a pathologist at Kowsar Laboratory, Tehran, Iran
Dr Hafezi is Professor of Plastic Surgery, Iran University of Medical Sciences, St Fatima Hospital, and Burn Research Center, Tehran, IranDr Abbaszadeh is a plastic surgery fellow, Iran University of Medical Sciences, St Fatima Hospital, and Burn Research Center, Tehran, IranDrs Ashtiani and Fatemi are Associate Professors of Plastic Surgery at the Iran University of Medical Sciences, St Fatima Hospital, and Burn Research Center, Tehran, IranDr Naghibzadeh is Professor of Ear, Nose, and Throat Surgery at Shahid Beheshty University of Medical Sciences, Loghman Hakim Hospital, Tehran, IranDr Nouhi is a pathologist at Kowsar Laboratory, Tehran, Iran.
出版信息
Aesthet Surg J. 2014 Sep;34(7):NP50-60. doi: 10.1177/1090820X14529076. Epub 2014 Apr 25.
BACKGROUND
Diced cartilage has been associated with several advantages and rewarding results, leading to its widespread application in various forms in rhinoplasty, but the outcomes of diced cartilage with and without tensor fascia latae wrapping have not been widely reported in evidence-based articles.
OBJECTIVES
The authors compared changes in weight, size, and histology of both bare and fascia-wrapped diced cartilage in rabbits as a model for human surgical outcomes.
METHODS
One auricle from each of 15 rabbits was divided into 2 pieces, and both samples were diced. The tensor fascia latae of the rabbit was wrapped around 1 cartilage specimen from each rabbit (group A specimen); the other specimen received no wrapping (group B specimen). A group A specimen and a group B specimen were implanted into separate subcutaneous pockets in each rabbit. After 3 months, samples were removed from the recipient beds and weighed to compare pre- and postoperative weights. All specimens were examined for evidence of cartilage viability by histologic methods.
RESULTS
There was a significant decrease in the weight of cartilage in group A. A nonsignificant weight increase was observed in group B. Histologic analyses of 5 parameters revealed no significant differences between the 2 groups, except for a significantly greater amount of new cartilage formation in group B.
CONCLUSIONS
Any type of wrapping around diced cartilage may inhibit its access to surrounding nutrients. Dicing increases the absorption surface, which may result in some overgrowth, but wrapping may have a negative impact on the viability of the diced cartilage.
LEVEL OF EVIDENCE
背景
切碎的软骨具有多种优势且效果良好，这使其在鼻整形术中以各种形式得到广泛应用，但切碎的软骨有无阔筋膜张肌包裹的效果在循证医学文献中尚未得到广泛报道。
目的
作者将兔体内裸露的和有筋膜包裹的切碎软骨的重量、大小及组织学变化进行比较，以此作为人类手术效果的模型。
方法
15只兔，每只兔的一个耳廓分成2块，将两块均切碎。把兔的阔筋膜张肌包裹在每只兔的1个软骨标本上（A组标本）；另一个标本不做包裹（B组标本）。将一个A组标本和一个B组标本植入每只兔的不同皮下囊袋中。3个月后，从受体床取出标本称重，比较术前和术后的重量。采用组织学方法检查所有标本，以确定软骨存活情况。
结果
A组软骨重量显著减轻。B组观察到重量有不显著的增加。对5项参数的组织学分析显示，两组之间无显著差异，但B组新软骨形成量显著更多除外。
结论
切碎的软骨周围的任何类型包裹都可能抑制其获取周围营养物质。切碎增加了吸收表面积，这可能导致一些过度生长，但包裹可能对切碎软骨的存活产生负面影响。
证据水平
4级。
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