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足部骨外软骨瘤——病例报告

Extraskeletal chondroma of the foot-a case report.

作者信息

Rajalakshmi V, Anand Venu, Ramprasad Narmada

机构信息

Professor and Head, Department of Pathology, ESIC -MC -PGIMSR , Chennai-78, India .

Professor and Head, Department of Plastic Surgery, Government Kilpauk Medical College , College, Chennai-10, India .

出版信息

J Clin Diagn Res. 2014 Mar;8(3):134-5. doi: 10.7860/JCDR/2014/7270.4135. Epub 2014 Mar 15.

Abstract

Extraskeletal Chondroma (ESC) is uncommon which occurs predominantly in hands and feet. It has a variable histology, with two thirds of the ESCs showing mature hyaline cartilage which is arranged in distinct lobules with fibrosis, or ossification, or myxoid areas and few showing immature patterns, with chondroblasts mimicking extraskeletal myxoid chondrosarcomas (ESMCSs). ESCs can recur but they never metastasize, whereas ESMCSs can metastasize, which require aggressive treatment. We are reporting a case of ESC which was located in the distal phalanx of right foot great toe in a 58-year-old male patient. The histopathology in our case showed features of ESC, with some foci showing myxoid stroma and few chondroblasts with atypical pleomorphic nuclei mimicking ESMCS. Hence, the case had to be carefully evaluated to exclude ESMCS and to make the diagnosis of ESC. The treatment was limited to simple excision of the tumour and extensive surgery and post operative radiotherapy were avoided.

摘要

骨外软骨瘤(ESC)较为罕见,主要发生于手足部位。其组织学表现多样,三分之二的骨外软骨瘤显示为成熟的透明软骨,呈明显的小叶状排列,伴有纤维化、骨化或黏液样区域,少数表现为不成熟的形态,有成软骨细胞,类似骨外黏液样软骨肉瘤(ESMCS)。骨外软骨瘤可复发,但从不转移,而骨外黏液样软骨肉瘤可转移,需要积极治疗。我们报告一例位于一名58岁男性患者右足大趾远节指骨的骨外软骨瘤病例。我们病例的组织病理学表现为骨外软骨瘤的特征,一些病灶显示黏液样间质,少数有成软骨细胞,核呈非典型多形性,类似骨外黏液样软骨肉瘤。因此,必须对该病例进行仔细评估,以排除骨外黏液样软骨肉瘤并诊断为骨外软骨瘤。治疗仅限于简单的肿瘤切除,避免了广泛手术和术后放疗。

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