[第三代β-肾上腺素能阻滞剂的肾保护特性]

[Nephroprotective properties of third-generation beta-adrenoblockers].

作者信息

Kuz'min O B, Belianin V V, Zhezha V V

出版信息

Eksp Klin Farmakol. 2014;77(3):40-3.

Abstract

Experimental and clinical data on the nephroprotector properties of third-generation beta-adrenoblockers nebivolol and carvedilol are reviewed. These properties are related to the antihypertensive effect and ability of drugs to suppress oxidative stress in glomerules, proximal renal tubules, and surrounding interstitial tissue.

摘要

综述了第三代β-肾上腺素能阻滞剂奈必洛尔和卡维地洛肾保护特性的实验和临床数据。这些特性与药物的降压作用以及抑制肾小球、近端肾小管和周围间质组织氧化应激的能力有关。