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原发性腕掌关节炎中掌骨间关节融合或伴有韧带重建的大多角骨切除术:一项随机对照试验。

Trapeziometacarpal arthrodesis or trapeziectomy with ligament reconstruction in primary trapeziometacarpal osteoarthritis: a randomized controlled trial.

机构信息

Hand Center, Isala klinieken Zwolle, Dr Van Heesweg 2, P.O. Box 10400, 8000 GK Zwolle, The Netherlands. E-mail address for G.M. Vermeulen:

Department of Plastic Surgery and Hand Surgery, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.

出版信息

J Bone Joint Surg Am. 2014 May 7;96(9):726-33. doi: 10.2106/JBJS.L.01344.

Abstract

BACKGROUND

Both trapeziectomy with ligament reconstruction and tendon interposition and trapeziometacarpal arthrodesis are commonly performed procedures for the treatment of trapeziometacarpal osteoarthritis. The purpose of this study was to compare the outcomes of both treatments for symptomatic osteoarthritis of the thumb trapeziometacarpal joint in a randomized trial.

METHODS

Women who were forty years of age or older were randomized either to trapeziectomy with ligament reconstruction and tendon interposition or to arthrodesis with plate and screws. Patients were evaluated preoperatively and at three and twelve months postoperatively with respect to pain, function (Patient-Rated Wrist/Hand Evaluation [PRWHE] and Disabilities of the Arm, Shoulder and Hand [DASH] questionnaires), joint motion, strength, complication rate, and patient satisfaction.

RESULTS

Forty-three patients were enrolled. Since we found significantly more moderate and severe complications following arthrodesis compared with trapeziectomy with ligament reconstruction and tendon interposition (71% versus 29%; p = 0.016), the study was prematurely terminated before the sample size necessary to validly compare the two groups was reached. The higher complication rate for arthrodesis led to an increase in revision surgery (two of seventeen patients). Significantly more patients in the ligament reconstruction and tendon interposition group (86%) than in the arthrodesis group (53%) indicated they would consider the same surgery again under the same circumstances (p = 0.025). In both groups, PRWHE and DASH scores significantly improved over time; however, comparison of the groups showed that the results were similar.

CONCLUSIONS

Women who are forty years or older with trapeziometacarpal osteoarthritis have fewer moderate and severe complications after trapeziectomy with ligament reconstruction and tendon interposition and are more likely to consider the surgery again under the same circumstances than are those who undergo arthrodesis. Twelve months after surgery, the PRWHE and DASH scores were similar in both groups. We do not recommend routine use of arthrodesis with plate and screws in the treatment of women who are forty years or older with stage-II or III trapeziometacarpal osteoarthritis.

摘要

背景

对于治疗腕掌关节(trapeziometacarpal joint)骨关节炎,掌骨间融合术(trapeziometacarpal arthrodesis)和韧带重建肌腱嵌入术(ligament reconstruction and tendon interposition)都是常用的治疗方法。本研究旨在通过随机试验比较这两种治疗方法治疗拇指腕掌关节(thumb trapeziometacarpal joint)症状性骨关节炎的效果。

方法

四十岁或以上的女性患者被随机分为掌骨间融合术组或韧带重建肌腱嵌入术组。患者分别在术前、术后 3 个月和 12 个月进行疼痛、功能(腕手评估患者评分[Patient-Rated Wrist/Hand Evaluation,PRWHE]和上肢残疾问卷[Disabilities of the Arm, Shoulder and Hand,DASH])、关节活动度、握力、并发症发生率和患者满意度评估。

结果

共纳入 43 名患者。由于我们发现掌骨间融合术的中重度并发症发生率显著高于韧带重建肌腱嵌入术(71%比 29%;p=0.016),因此在达到有效比较两组所需的样本量之前,该研究提前终止。掌骨间融合术较高的并发症发生率导致了更多的翻修手术(17 名患者中有 2 人)。在韧带重建肌腱嵌入术组中,有 86%的患者表示在相同情况下会再次考虑接受相同的手术,而在掌骨间融合术组中这一比例为 53%(p=0.025)。两组患者的 PRWHE 和 DASH 评分均随时间显著改善,但组间比较显示结果相似。

结论

四十岁或以上患有腕掌关节骨关节炎的女性患者行韧带重建肌腱嵌入术的中重度并发症较少,且在相同情况下再次接受手术的可能性高于行掌骨间融合术的患者。术后 12 个月,两组的 PRWHE 和 DASH 评分相似。我们不建议常规使用掌骨间融合术加钢板螺钉治疗四十岁或以上、处于 II 期或 III 期的腕掌关节骨关节炎女性患者。

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