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肝硬化患者的非肝脏胃肠道手术

Non-hepatic gastrointestinal surgery in patients with cirrhosis.

作者信息

Sabbagh C, Fuks D, Regimbeau J-M

机构信息

Department of digestive and oncological surgery, hôpital Nord, place Victor-Pauchet, 80054 Amiens cedex 01, France.

Department of digestive and oncological surgery, hôpital Nord, place Victor-Pauchet, 80054 Amiens cedex 01, France.

出版信息

J Visc Surg. 2014 Jun;151(3):203-11. doi: 10.1016/j.jviscsurg.2014.04.004. Epub 2014 May 5.

Abstract

Gastrointestinal surgery is feasible in patients with Child A cirrhosis, but is associated with higher morbidity and mortality. Hernia repair, biliary and colonic surgery are the most frequently performed interventions in this context. Esophageal and pancreatic surgery are more controversial and less frequently performed. For patients with decompensated liver function (Child B or C patients), the indications for surgery should be discussed by a multi-specialty team including the hepatologist, anesthesiologist, surgeon; liver function should be optimized if possible. During emergency surgery, histologic diagnosis of cirrhosis should be confirmed by liver biopsy because the histologic diagnosis has therapeutic and prognostic implications. The management of patients with Child A cirrhosis without portal hypertension is little different from the management of patients without cirrhosis. However, the management of patients with Child B or C cirrhosis or with portal hypertension is more complex and requires an accurate assessment of the balance of benefit vs. risk for surgical intervention on a case-by-case basis.

摘要

对于Child A级肝硬化患者,胃肠手术是可行的,但会伴有较高的发病率和死亡率。在此情况下,疝修补术、胆道和结肠手术是最常施行的干预措施。食管和胰腺手术则更具争议性,且施行频率较低。对于肝功能失代偿的患者(Child B级或C级患者),应由包括肝病学家、麻醉师、外科医生在内的多专科团队讨论手术指征;如有可能,应优化肝功能。在急诊手术期间,肝硬化的组织学诊断应通过肝活检来证实,因为组织学诊断具有治疗和预后意义。无门静脉高压的Child A级肝硬化患者的管理与无肝硬化患者的管理差别不大。然而,Child B级或C级肝硬化患者或有门静脉高压患者的管理更为复杂,需要根据具体情况准确评估手术干预的获益与风险平衡。

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