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寰枢椎脱位伴基底凹陷的治疗:经口寰枢椎复位钢板(TARP)行寰枢关节撑开与固定,无需切除齿突。

Treatment of basilar invagination with atlantoaxial dislocation: atlantoaxial joint distraction and fixation with transoral atlantoaxial reduction plate (TARP) without odontoidectomy.

作者信息

Xia Hong, Yin QingShui, Ai FuZhi, Ma XiangYang, Wang JianHua, Wu ZengHui, Zhang Kai, Liu JingFa, Xu JunJie

机构信息

Department of Orthopedics, Guangzhou General Hospital of Guangzhou Military Command (Liuhuaqiao Hospital), No.111 Liuhua Avenue, Guangzhou, People's Republic of China,

出版信息

Eur Spine J. 2014 Aug;23(8):1648-55. doi: 10.1007/s00586-014-3378-8. Epub 2014 May 18.

Abstract

PURPOSE

Although direct transoral decompression and one-stage posterior instrumentation can obtain satisfactory cord decompression for the treatment of basilar invagination with atlantoaxial dislocation, surgical injuries run high as combinative anterior-posterior approaches were necessary. Furthermore, the complications will rise notably when involvement of dens and/or clivus in the decompression necessitates relatively complicated surgical techniques. First initiated in 2005, transoral atlantoaxial reduction plate (TARP) works as an internal fixation for the treatment of basilar invagination with irreducible atlantoaxial dislocation. Therefore, this article aimed to describe several operative experiences about this approach, which has delivered successful decompression, fixation and fusion.

METHODS

21 consecutive patients with basilar invagination underwent the TARP operation. The pre- and postoperative medulla-cervical angles were measured and compared. The JOA scores of spinal cord function were calculated pre- and post-operatively. 20 cases (20/21) were followed up to average 12.5 months.

RESULTS

Symptoms of all the 20 cases were relieved in different degrees. The postoperative imaging showed the odontoid processes obtained ideal reduction and the internal fixators were all in good position. The medulla-cervical angle was correctd from an average (± standard deviation) 128.7° + 11.9° (n = 20) before surgery to 156.5° + 8.1° (n = 20) after surgery (P < 0.01). The average preoperative and postoperative Japaneses Orthopedic Association scores were 11.25 (n = 20) and 15.9 (n = 20), respectively, indicating 76 % improvement. Screw-loosening was observed in one patient due to severe osteoporosis. After a revised operation with a TARP in another size, the neurological symptoms showed no obvious improvements. Then the treatment was terminated.

CONCLUSIONS

The TARP operation and intra-operative traction could reduce the odontoid process superiorly migrating into the foramen magnum, directly ease the ventral compression of spinal cord, and fix the reduced atlantoaxial joints through a single transoral approach without the need of a posterior operation. In this stury, 21 patients were evaluated and 20 did well with TARP operation. The preliminary clinical result was satisfactory.

摘要

目的

尽管直接经口减压和一期后路内固定术可获得满意的脊髓减压效果,用于治疗伴有寰枢椎脱位的基底凹陷症,但由于需要联合前后路手术,手术损伤风险较高。此外,当减压过程中涉及齿突和/或斜坡时,需要相对复杂的手术技术,并发症也会显著增加。经口寰枢椎复位钢板(TARP)于2005年首次应用,可作为一种内固定装置用于治疗伴有不可复位寰枢椎脱位的基底凹陷症。因此,本文旨在描述该手术方法的一些手术经验,该方法已成功实现减压、固定和融合。

方法

21例连续的基底凹陷症患者接受了TARP手术。测量并比较术前和术后延髓-颈椎角。计算术前和术后脊髓功能JOA评分。20例(20/21)患者获得随访,平均随访时间为12.5个月。

结果

20例患者的症状均有不同程度缓解。术后影像学检查显示齿突获得理想复位,内固定器位置良好。延髓-颈椎角由术前平均(±标准差)128.7° + 11.9°(n = 20)矫正至术后156.5° + 8.1°(n = 20)(P < 0.01)。术前和术后日本骨科协会评分的平均值分别为11.25(n = 20)和15.9(n = 20),改善率为76%。1例患者因严重骨质疏松出现螺钉松动。在更换另一尺寸的TARP进行翻修手术后,神经症状无明显改善。随后终止治疗。

结论

TARP手术及术中牵引可使齿突向上移位进入枕骨大孔,直接减轻脊髓腹侧压迫,并通过单一经口入路固定复位后的寰枢关节,无需后路手术。在本研究中,对21例患者进行了评估,20例患者接受TARP手术效果良好。初步临床结果令人满意。

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