粪便微生物群移植用于复发性艰难梭菌感染儿童
Fecal microbiota transplantation in children with recurrent Clostridium difficile infection.
作者信息
Pierog Anne, Mencin Ali, Reilly Norelle Rizkalla
机构信息
From the Columbia University Medical Center, Division of Pediatric Gastroenterology, Hepatology and Nutrition, New York, NY.
出版信息
Pediatr Infect Dis J. 2014 Nov;33(11):1198-200. doi: 10.1097/INF.0000000000000419.
Clostridium difficile eradication using fecal microbiota transplantation (FMT) has been successful in adults but little information is available in pediatrics. We report 6 pediatric patients with refractory C. difficile cured by FMT with no recurrences to date. Our results demonstrate that FMT can be an effective treatment for refractory C. difficile infection in pediatrics. Long-term safety and efficacy need to be studied.
使用粪便微生物群移植（FMT）根除艰难梭菌在成人中已取得成功，但儿科方面的信息较少。我们报告了6例难治性艰难梭菌感染的儿科患者通过FMT治愈，至今无复发。我们的结果表明，FMT可以作为儿科难治性艰难梭菌感染的一种有效治疗方法。其长期安全性和疗效有待研究。
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