Memish Ziad A, Cotten Matthew, Meyer Benjamin, Watson Simon J, Alsahafi Abdullah J, Al Rabeeah Abdullah A, Corman Victor Max, Sieberg Andrea, Makhdoom Hatem Q, Assiri Abdullah, Al Masri Malaki, Aldabbagh Souhaib, Bosch Berend-Jan, Beer Martin, Müller Marcel A, Kellam Paul, Drosten Christian
Emerg Infect Dis. 2014 Jun;20(6):1012-5. doi: 10.3201/eid2006.140402.
We investigated a case of human infection with Middle East respiratory syndrome coronavirus (MERS-CoV) after exposure to infected camels. Analysis of the whole human-derived virus and 15% of the camel-derived virus sequence yielded nucleotide polymorphism signatures suggestive of cross-species transmission. Camels may act as a direct source of human MERS-CoV infection.
我们调查了一例人类在接触感染骆驼后感染中东呼吸综合征冠状病毒(MERS-CoV)的病例。对全人类源病毒和15%的骆驼源病毒序列进行分析,发现了提示跨物种传播的核苷酸多态性特征。骆驼可能是人类感染MERS-CoV的直接来源。