Včelák Josef, Chomiak Jiří, Toth Ladislav
Department of Orthopedics, 1st Medical Faculty of Charles University and Hospital Na Bulovce, Prague, Czech Republic.
Int Orthop. 2014 Jul;38(7):1425-34. doi: 10.1007/s00264-014-2360-8. Epub 2014 May 24.
This study evaluates two basic hypotheses: (1) the risk of an isolated dorsal approach to ventral lumbar spondylodiscitis based on clinical and radiographic results and (2) the risk of anterior radical debridement due to using a titanium implant in the site of bone infection.
Group A consisting of 23 patients was treated only by a dorsal transmuscular approach and group B consisting of eight patients was treated by two-stage posteroanterior surgery. Both evaluated groups were assessed before surgery, six weeks and one year after surgery with the Japanese Orthopaedic Association (JOA) score, visual analogue scale (VAS) and Kirkaldy-Willis functional criteria. To evaluate the sagittal balance restoration, measurement by the Cobb modified angle of the affected segment was performed.
Differences (p < 0.001) in group A were found between JOA values before surgery (average 9.30) and at six weeks after surgery (average 11.82) and 12 months after surgery (13.27) and VAS differences before surgery (average 7.39), six weeks after surgery (average 3.82) and 12 months after surgery (average 2.36) in group A. According to the Kirkaldy-Willis functional criteria, 11 patients were evaluated as excellent, nine patients as good and two patients as poor. The values of the JOA score in group B showed an improvement compared with the JOA values before surgery (average 9.38) at six weeks after surgery (average 11.75) and 12 months after surgery (average 13.63), and the VAS score before surgery (average 7.38) was found to have improved six weeks after surgery (average 4.63) and 12 months after surgery (average 2.25). The functional evaluation according to the Kirkaldy-Willis functional criteria assessed three patients as excellent, four patients as good and one patient as fair. Radiographic examinations of group A revealed the following findings before surgery (average 1.75), six months after surgery (average -3.73) and 12 months after surgery (average -0.79) and in group B before surgery (average 3.71), six weeks after surgery (average -8.21) and 12 months after surgery (average -6.45).
The results demonstrate the minimum serious surgical complications and greater loss of sagittal balance without clinical correlation in group A. We did not find any relapse or persistence of the infection in the post-operative period in group B.
本研究评估两个基本假设:(1)基于临床和影像学结果,单纯采用后路入路治疗腰椎腹侧椎体椎间盘炎的风险;(2)在骨感染部位使用钛植入物导致前路根治性清创的风险。
A组由23例患者组成,仅采用经肌肉后路入路治疗,B组由8例患者组成,采用两阶段前后路联合手术治疗。两组均在手术前、术后6周和1年进行评估,采用日本骨科协会(JOA)评分、视觉模拟量表(VAS)和Kirkaldy-Willis功能标准。为评估矢状面平衡恢复情况,对患节段进行Cobb改良角测量。
A组术前JOA值(平均9.30)与术后6周(平均11.82)及术后12个月(13.27)之间存在差异(p<0.001),术前VAS值(平均7.39)、术后6周(平均3.82)及术后12个月(平均2.36)之间也存在差异。根据Kirkaldy-Willis功能标准,11例患者评估为优,9例患者评估为良,2例患者评估为差。B组JOA评分值与术前JOA值(平均9.38)相比,术后6周(平均11.75)及术后12个月(平均13.63)有所改善,术前VAS评分(平均7.38)在术后6周(平均4.63)及术后12个月(平均2.25)有所改善。根据Kirkaldy-Willis功能标准进行的功能评估,3例患者评估为优,4例患者评估为良及1例患者评估为中。A组术前(平均1.75)、术后6个月(平均-3.73)及术后12个月(平均-0.79)的影像学检查结果,以及B组术前(平均3.71)、术后6周(平均-8.21)及术后12个月(平均-6.45)的影像学检查结果。
结果表明,A组手术严重并发症最少,但矢状面平衡丧失较大且与临床无关。B组术后未发现感染复发或持续存在。