Krishna Senthil G, Ramesh Archana S, Jatana Kris R, Elmaraghy Charles, Merz Meredith, Ruda James, Tobias Joseph D
Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA; Department of Anesthesiology, the Ohio State University, Columbus, OH, USA.
Paediatr Anaesth. 2014 Sep;24(9):999-1004. doi: 10.1111/pan.12437. Epub 2014 May 24.
A major concern with the use of cuffed endotracheal tubes (cETT) in children is hyperinflation of the cuff which may compromise tracheal mucosal perfusion. To measure the intracuff pressure (CP), we devised a method using the transducer of an invasive pressure monitoring device. The objective of the study was to test the accuracy and validity of this device for instantaneous and continuous CP monitoring.
The study was conducted in 2 phases. In Phase 1 (200 pediatric patients), after inflation of the cuff, the CP was measured using the standard manometer and the transducer simultaneously. In Phase 2 (20 pediatric patients), the transducer was left connected to the pilot balloon of the ETT to obtain a continuous CP reading and the standard manometer was used to measure the CP at 5-min intervals. Statistical analysis included a Bland-Altman comparison and linear regression analysis.
In Phase 1, linear regression analysis demonstrated an R2 value of 0.9956. The bias was 0.30 cmH2O, the precision was 0.75 cmH2O, and the 95% level of agreement (LOA) ranged from -1.16 to 1.77 cmH2O. In Phase 2, the linear regression analysis revealed an R2 value of 0.9846. The bias was 0.28 cmH2O, the precision was 0.7 cmH2O, and the 95% LOA ranged from -1.1 to 1.66 cmH2O.
Our study demonstrates that when cETTs are used in the pediatric population, the transducer of the invasive pressure monitoring device can be used reliably to measure the CP at the time of inflation and continuously thereafter.
在儿童中使用带套囊气管内导管(cETT)的一个主要问题是套囊过度充气,这可能会损害气管黏膜灌注。为了测量套囊内压力(CP),我们设计了一种使用有创压力监测设备的传感器的方法。本研究的目的是测试该设备用于即时和连续CP监测的准确性和有效性。
研究分两个阶段进行。在第一阶段(200例儿科患者),套囊充气后,同时使用标准压力计和传感器测量CP。在第二阶段(20例儿科患者),将传感器连接到ETT的 pilot 球囊上以获得连续的CP读数,并使用标准压力计每隔5分钟测量一次CP。统计分析包括Bland-Altman比较和线性回归分析。
在第一阶段,线性回归分析显示R2值为0.9956。偏差为0.30 cmH2O,精密度为0.75 cmH2O,95%一致性界限(LOA)范围为-1.16至1.77 cmH2O。在第二阶段,线性回归分析显示R2值为0.9846。偏差为0.28 cmH2O,精密度为0.7 cmH2O,95% LOA范围为-1.1至1.66 cmH2O。
我们的研究表明,当在儿科人群中使用cETT时,有创压力监测设备的传感器可可靠地用于在充气时测量CP,并在此后持续测量。