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一名年轻男性发生的异时性双侧睾丸粒细胞肉瘤:一例罕见病例报告

Metachronous bilateral granulocytic sarcoma of the testis in a young adult: a report of an unusual entity.

作者信息

Hızlı Fatih, Aksüt Hakan, Mengeloğlu Aslı, Sarı Ibrahim, Güven Eşref Oğuz, Başar Halil

机构信息

Department of Urology, Oncology Training and Research Hospital, Demetevler, 06530 Ankara, Turkey.

Department of Urology, Kilis State Hospital, Kilis, Turkey.

出版信息

Case Rep Urol. 2014;2014:762630. doi: 10.1155/2014/762630. Epub 2014 May 6.

Abstract

Granulocytic sarcomas are rare tumors composed of neoplastic blood cells, typically occurring during the course of acute nonlymphoblastic leukemia or before its onset. We present a case of a 23-year-old young adult man with metachronous granulocytic sarcoma of the testis without hematologic manifestations who was diagnosed with granulocytic sarcoma (GS). The patient was treated with right orchiectomy but relapsed with a left testicular mass 16 months later when a left orchiectomy was performed. The patient has been free of disease for 13 months following the left orchiectomy. This case highlights a rare hematologic cancer that urologists and pathologists should be aware of since it can present as a testicular mass. Only 3 cases of testicular GS without an associated hematologic disorder have been described. To the best of our knowledge, our patient is the first reported case in the English literature of metachronous GS of the testis with no evidence of hematologic disorder.

摘要

粒细胞肉瘤是由肿瘤性血细胞组成的罕见肿瘤,通常发生在急性非淋巴细胞白血病病程中或其发病之前。我们报告一例23岁青年男性病例,该患者患有睾丸异时性粒细胞肉瘤,无血液学表现,被诊断为粒细胞肉瘤(GS)。患者接受了右侧睾丸切除术,但16个月后左侧睾丸出现肿块复发,遂进行了左侧睾丸切除术。左侧睾丸切除术后患者已无病生存13个月。该病例突出了一种罕见的血液系统癌症,泌尿外科医生和病理科医生应予以关注,因为它可能表现为睾丸肿块。仅报道过3例无相关血液系统疾病的睾丸GS病例。据我们所知,我们的患者是英文文献中首例报道的无血液系统疾病证据的睾丸异时性GS病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6405/4026881/47e4f4ce367b/CRIU2014-762630.001.jpg

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