Lkhoyaali Sihame, Boutayeb Saber, Ismaili Nabil, Aitelhaj Meriem, Ouchen Fahd, Benosman Abdellatif, Errihani Hassan
Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
BMC Res Notes. 2014 May 5;7:283. doi: 10.1186/1756-0500-7-283.
Fetal adenocarcinoma of the lung is a rare subtype of pulmonary adenocarcinoma with a relative estimated incidence of 0.5% or fewer of all lung cancers. Because of its extreme rarity, there have been no controlled clinical trials investigating treatment regimens for fetal adenocarcinoma and, as a result, there are no guidelines for management.
We report a case of a well-differentiated fetal adenocarcinoma, which is a variant of pulmonary blastoma, that is a low-grade malignancy and associated with a good prognosis. A 29-year-old Moroccan man presented with a well-differentiated fetal adenocarcinoma staged T3N0M0, who received 3 cycles of neoadjuvant chemotherapy followed by surgery, with no recurrence at 2 years follow-up.
Fetal adenocarcinoma is a rare suptype of adenocarcinoma. Surgical resection is the treatment of choice for resectable disease. The role of chemotherapy in the neoadjuvant setting or adjuvant setting is not well defined.
胎儿型肺腺癌是肺腺癌的一种罕见亚型，估计在所有肺癌中的发病率相对为0.5%或更低。由于其极为罕见，尚无关于胎儿型腺癌治疗方案的对照临床试验，因此也没有管理指南。
我们报告一例高分化胎儿型腺癌病例，它是肺母细胞瘤的一种变体，为低级别恶性肿瘤且预后良好。一名29岁的摩洛哥男子被诊断为高分化胎儿型腺癌，分期为T3N0M0，接受了3个周期的新辅助化疗，随后进行了手术，在2年的随访中无复发。
胎儿型腺癌是腺癌的一种罕见亚型。手术切除是可切除疾病的首选治疗方法。化疗在新辅助或辅助治疗中的作用尚不明确。
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