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剖宫产瘢痕绒毛膜癌:病例报告及文献复习。

Caesarean scar choriocarcinoma: a case report and review of the literature.

机构信息

Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University, 1 Xueshi Road, Hangzhou, Zhejiang Province 310006, People's Republic of China.

出版信息

Eur J Med Res. 2014 May 14;19(1):25. doi: 10.1186/2047-783X-19-25.

Abstract

OBJECTIVE

To report the clinical characteristics, pathologic findings and treatments of a patient with a Caesarean scar choriocarcinoma.

PATIENT HISTORY

A 22-year-old woman had a diagnosis of primary gestational choriocarcinoma in a uterine Caesarean scar misdiagnosed as a normal Caesarean scar pregnancy. The patient underwent selective uterine artery embolization coupled with methotrexate arterial injection, along with dilatation and curettage of the uterine Caesarean scar. Finally, she received eight courses of multiagent chemotherapy. The reproductive function of the patient was preserved.

CONCLUSIONS

Primary gestational choriocarcinoma out of the uterine corpus is a rare disease. A Caesarean scar choriocarcinoma is an extremely unusual example of this entity because of its unique position. To the best of our knowledge, this is the first report of this phenomenon. Our experience and a literature review suggest that a clinical diagnosis of a primary gestational choriocarcinoma of the uterine Caesarean scar is difficult to make, and uterine artery embolization is beneficial to prevent massive bleeding before curettage.

摘要

目的

报告 1 例剖宫产瘢痕部位妊娠绒癌患者的临床特点、病理发现和治疗经过。

患者病史

1 名 22 岁女性,因剖宫产子宫瘢痕妊娠误诊为正常剖宫产瘢痕妊娠而被诊断为原发性妊娠绒癌。该患者接受了选择性子宫动脉栓塞术联合甲氨蝶呤动脉注射、剖宫产子宫瘢痕扩宫及刮宫术。最终,她接受了 8 个疗程的多药化疗。患者保留了生殖功能。

结论

原发性妊娠绒癌来源于子宫体是一种罕见疾病。剖宫产瘢痕绒癌是该疾病的一种极不常见的表现形式,因为其位置独特。据我们所知,这是首例此类病例报道。我们的经验和文献复习提示,临床诊断剖宫产子宫瘢痕部位妊娠绒癌较为困难,子宫动脉栓塞术有利于在刮宫术前行预防性止血。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16ec/4026121/b15cea7f3fb7/2047-783X-19-25-1.jpg

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