Nishida Masato, Ichikawa Ryota, Arai Yuko, Sakanaka Miyako, Otsubo Yasuo
Department of Obstetrics and Gynecology, National Hospital Organization, Kasumigaura Medical Center, Ibaraki, Japan.
J Obstet Gynaecol Res. 2014 Jun;40(6):1689-94. doi: 10.1111/jog.12382.
The aim of this study was to determine the effects of a new myomectomy technique for diffuse uterine leiomyomatosis.
To enucleate multiple myomas, we developed a novel myomectomy technique involving longitudinal dissection of the uterus in the midline. On each side of the anterior and posterior walls, the uterine wall was further divided into two pieces from the incision site. Myomas were separated into serosal and mucosal sides, and then enucleated for removal from the thinned myometrium.
This procedure was applied for seven patients with diffuse leiomyomatosis. The mean number of myomas enucleated from each patient was 117 (range, 74-226). Mean total weight of enucleated myomas was 147.6 g (range, 59-360 g). Mean operative time was 284 min (range, 212-407 min). Mean blood loss was 1614 g (range, 428-4421 g), with three patients requiring blood transfusion. Anemia due to menorrhagia improved in all women. Three patients became pregnant, with two undergoing cesarean section after a normal course of pregnancy and giving birth to healthy babies. The third pregnancy ended in miscarriage. We noticed intraoperatively that myoma nodules were connected to each other in every case.
This procedure should be considered as a therapeutic option in women suffering from symptoms of diffuse uterine leiomyomatosis who wish to avoid hysterectomy.
本研究旨在确定一种用于弥漫性子宫平滑肌瘤病的新肌瘤切除术技术的效果。
为了摘除多个肌瘤,我们开发了一种新的肌瘤切除术技术,该技术包括在子宫中线进行纵向切开。在前壁和后壁的每一侧,子宫壁从切口部位进一步分成两片。肌瘤被分离到浆膜侧和黏膜侧,然后从变薄的肌层中摘除。
该手术应用于7例弥漫性平滑肌瘤病患者。每位患者摘除的肌瘤平均数量为117个(范围为74 - 226个)。摘除肌瘤的平均总重量为147.6克(范围为59 - 360克)。平均手术时间为284分钟(范围为212 - 407分钟)。平均失血量为1614克(范围为428 - 4421克),3例患者需要输血。所有女性因月经过多导致的贫血均有所改善。3例患者怀孕,其中2例在正常妊娠过程后接受剖宫产并产下健康婴儿。第三例妊娠以流产告终。我们在手术中注意到,每例病例中的肌瘤结节相互连接。
对于希望避免子宫切除术且患有弥漫性子宫平滑肌瘤病症状的女性,应考虑将该手术作为一种治疗选择。