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[我国近年来所见的食源性肉毒中毒及其流行病学特征]

[Food-borne botulism and its epidemiological features as seen in our country during the last few years].

作者信息

Onul M, Willke A

机构信息

Ankara Universitesi, Tip Fakültesi, Klinik Bakteriyoloji ve Infeksiyon Hastaliklari Anabilim Dali.

出版信息

Mikrobiyol Bul. 1989 Oct;23(4):284-91.

PMID:2488935
Abstract

We evaluated and presented here, the features of the eleven cases of food-borne botulism who admitted to the Infectious Diseases Department of Ibni Sina Hospital of Ankara University. Three of the cases admitted in 1984 and eight of them admitted in 1987. All of the cases were caused by home-prepared foods which had been eaten without cooking; the types of the food were green beans and pepper with sauce. In these cases the main symptoms and signs were generalized muscular weakness, dry mouth, dysphagia, diplopia, ptosis of the eyelids; besides these the other clinical symptoms and signs were seen in some patients. Although toxin couldn't be detected in the patients' sera by mouse-toxin neutralization, the EMG findings supported our diagnoses. To the three patients in the first group, botulinal anti-toxin was not given and two of them died. Anti-toxin was administered to the seven patients in the second group, none of them died.

摘要

我们在此评估并呈现了安卡拉大学伊本·西那医院传染病科收治的11例食源性肉毒中毒病例的特征。其中3例于1984年入院,8例于1987年入院。所有病例均由未经烹饪就食用的自制食品引起;食物种类为青豆和带酱汁的辣椒。这些病例的主要症状和体征为全身肌肉无力、口干、吞咽困难、复视、眼睑下垂;除此之外,部分患者还出现了其他临床症状和体征。尽管通过小鼠毒素中和试验未能在患者血清中检测到毒素,但肌电图检查结果支持我们的诊断。第一组的3例患者未接受肉毒抗毒素治疗,其中2例死亡。第二组的7例患者接受了抗毒素治疗,无一例死亡。

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