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克罗恩病的诊断影像学:新的金标准是什么?

Diagnostic imaging in Crohn's disease: what is the new gold standard?

机构信息

Department of Radiology, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.

Department of Radiology, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.

出版信息

Best Pract Res Clin Gastroenterol. 2014 Jun;28(3):421-36. doi: 10.1016/j.bpg.2014.04.010. Epub 2014 May 5.

Abstract

Historically Barium and isotope studies been used for imaging of inflammatory bowel disease (IBD) but carry risk of radiation exposure. Use of Barium is declining resulting in fewer radiologists that have the necessary expertise. Isotopes studies lack anatomical definition but 18F - fludeoxyglucose (FDG) positron emission tomography (PET) shows promise in accurate assessment of disease compared to endoscopy. Computerised tomography (CT) is particularly useful in assessment of complications of Crohn's disease (CD) but radiation exposure is high. CT enterography (CTE) has improved visualisation of small bowel mucosal disease and allows assessment of disease activity. Ultrasound is increasingly used for preliminary assessment of patients with potential IBD. Although widely available and economically attractive, the expertise required is not widespread. Finally magnetic resonance imaging (MRI) is proving to be the most accurate tool for assessment of disease extent and distribution. MRI of the pelvis has superseded other techniques in assessment of peri-anal fistulation.

摘要

从历史上看,钡和同位素研究曾被用于炎症性肠病 (IBD) 的成像,但存在辐射暴露的风险。钡的使用正在减少,导致具有必要专业知识的放射科医生越来越少。同位素研究缺乏解剖定义,但 18F-氟脱氧葡萄糖 (FDG) 正电子发射断层扫描 (PET) 在疾病的准确评估方面显示出优于内窥镜检查的潜力。计算机断层扫描 (CT) 在评估克罗恩病 (CD) 的并发症方面特别有用,但辐射暴露量很高。CT 肠造影 (CTE) 提高了小肠黏膜疾病的可视化程度,并允许评估疾病活动度。超声越来越多地用于初步评估有潜在 IBD 的患者。尽管超声广泛可用且具有经济吸引力,但所需的专业知识并不广泛。最后,磁共振成像 (MRI) 被证明是评估疾病程度和分布的最准确工具。盆腔 MRI 在评估肛周瘘管方面已取代了其他技术。

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