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急性冠状动脉综合征住院患者二级预防药物处方、生活方式建议和康复转介:来自澳大利亚和新西兰大型前瞻性审计的结果。

Prescription of secondary prevention medications, lifestyle advice, and referral to rehabilitation among acute coronary syndrome inpatients: results from a large prospective audit in Australia and New Zealand.

机构信息

The George Institute for Global Health, Sydney, Australia Sydney Medical School, University of Sydney, Sydney, Australia.

Department of Cardiovascular Medicine, Flinders University, Southern Adelaide Local Health Network, Adelaide, Australia.

出版信息

Heart. 2014 Aug;100(16):1281-8. doi: 10.1136/heartjnl-2013-305296. Epub 2014 Jun 9.

Abstract

OBJECTIVE

To evaluate the proportion of patients hospitalised with acute coronary syndrome (ACS) in Australia and New Zealand who received optimal inpatient preventive care and to identify factors associated with preventive care.

METHODS

All patients hospitalised bi-nationally with ACS were identified between 14-27 May 2012. Optimal in-hospital preventive care was defined as having received lifestyle advice, referral to rehabilitation, and prescription of secondary prevention pharmacotherapies. Multilevel multivariable logistic regression was used to determine factors associated with receipt of optimal preventive care.

RESULTS

For the 2299 ACS survivors, mean (SD) age was 69 (13) years, 46% were referred to rehabilitation, 65% were discharged on sufficient preventive medications, and 27% received optimal preventive care. Diagnosis of ST elevation myocardial infarction (OR: 2.64 [95% CI: 1.88-3.71]; p<0.001) and non-ST elevation myocardial infarction (OR: 1.99 [95% CI: 1.52-2.61]; p<0.001) compared with a diagnosis of unstable angina, having a percutaneous coronary intervention (PCI) (OR: 4.71 [95% CI: 3.67-6.11]; p<0.001) or coronary bypass (OR: 2.10 [95% CI: 1.21-3.60]; p=0.011) during the admission or history of hypertension (OR:1.36 [95% CI: 1.06-1.75]; p=0.017) were associated with greater exposure to preventive care. Age over 70 years (OR:0.53 [95% CI: 0.35-0.79]; p=0.002) or admission to a private hospital (OR:0.59 [95% CI: 0.42-0.84]; p=0.003) were associated with lower exposure to preventive care.

CONCLUSIONS

Only one-quarter of ACS patients received optimal secondary prevention in-hospital. Patients with UA, who did not have PCI, were over 70 years or were admitted to a private hospital, were less likely to receive optimal care.

摘要

目的

评估澳大利亚和新西兰因急性冠状动脉综合征(ACS)住院患者接受最佳住院预防保健的比例,并确定与预防保健相关的因素。

方法

2012 年 5 月 14 日至 27 日,在两国范围内确定所有因 ACS 住院的患者。最佳住院预防保健定义为接受生活方式建议、康复转介和开具二级预防药物治疗。采用多水平多变量逻辑回归分析确定与接受最佳预防保健相关的因素。

结果

在 2299 名 ACS 幸存者中,平均(SD)年龄为 69(13)岁,46%的患者被转介至康复机构,65%的患者出院时开具了足够的预防药物,27%的患者接受了最佳预防保健。与不稳定型心绞痛相比,ST 段抬高型心肌梗死(OR:2.64[95%CI:1.88-3.71];p<0.001)和非 ST 段抬高型心肌梗死(OR:1.99[95%CI:1.52-2.61];p<0.001)的诊断、经皮冠状动脉介入治疗(OR:4.71[95%CI:3.67-6.11];p<0.001)或冠状动脉旁路移植术(OR:2.10[95%CI:1.21-3.60];p=0.011)的入院期间或有高血压史(OR:1.36[95%CI:1.06-1.75];p=0.017)与接受更多预防保健相关。70 岁以上(OR:0.53[95%CI:0.35-0.79];p=0.002)或入住私立医院(OR:0.59[95%CI:0.42-0.84];p=0.003)与接受预防保健的可能性降低相关。

结论

只有四分之一的 ACS 患者接受了最佳的院内二级预防。UA 患者、未行 PCI、年龄超过 70 岁或入住私立医院,不太可能接受最佳治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abb8/4112453/7ef0f441a948/heartjnl-2013-305296f01.jpg

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