Qayyum T, Willder J M, McArdle P A, Horgan P G, Edwards J, Underwood M A
Unit of Experimental Therapeutics, Institute of Cancer, College of MVLS, University of Glasgow, Western Infirmary, Glasgow, UK.
Department of Urology, Royal Infirmary, Glasgow, UK.
Curr Urol. 2013 Nov;7(2):62-4. doi: 10.1159/000356250. Epub 2013 Oct 30.
The aim of this study was to examine the accuracy of standard magnetic resonance imaging (MRI) in the localised staging of prostate cancer in those who had undergone radical prostatectomy.
The cohort consisted of 110 patients who had undergone MRI for staging of prostate cancer and subsequently underwent radical prostatectomy. T stage was analysed both on MRI and from the specimen following radical surgery.
Of the patients 57% of patients had their disease up-staged following radical surgery from preoperative MRI findings. Of those patients who had their disease up-staged following surgery, nearly 50% of patients had gone from organ confined disease at time of MRI to extra-prostatic involvement from the surgical specimen.
We have reported that MRI has a wide range of accuracy. Given developments in MRI technologies further work should be pursued to help in the staging of this disease for which decision to treat is difficult.
本研究旨在检验标准磁共振成像(MRI)在接受根治性前列腺切除术患者的前列腺癌局部分期中的准确性。
该队列由110例接受MRI前列腺癌分期并随后接受根治性前列腺切除术的患者组成。对MRI上的T分期以及根治性手术后标本的T分期进行了分析。
在这些患者中,57%的患者在根治性手术后,根据术前MRI结果其疾病分期被上调。在那些术后疾病分期被上调的患者中,近50%的患者在MRI检查时为局限于器官内的疾病,而手术标本显示为前列腺外侵犯。
我们报告MRI具有广泛的准确性。鉴于MRI技术的发展,应进一步开展工作以帮助对这种难以做出治疗决策的疾病进行分期。