影响癌症青少年和年轻患者转至试验参与率较高的治疗点。
Influencing referral of adolescents and young adults with cancer to sites with higher rates of trial enrollment.
机构信息
Cook Children's Medical Center, Fort Worth, Texas;Department of Pediatrics, University of North Texas Health Science Center, Fort Worth, Texas; and
Department of Pediatrics, University of Nebraska Medical Center, Omaha, Nebraska.
出版信息
Pediatrics. 2014 Jun;133 Suppl 3:S104-8. doi: 10.1542/peds.2014-0122E.
Adolescents and young adults (AYAs) have lower rates of clinical trial enrollment than younger or older patients with cancer. Multiple approaches to change policy and practice need to be used to improve this statistic. This article examines the option of increasing referral to 3 types of centers that are known to have relatively higher rates of enrollment of AYAs: pediatric cancer centers, AYA oncology programs, and National Cancer Institute-designated cancer centers. There are reasonable challenges to changing referral patterns, and more research, as well as education of those diagnosing AYAs, is required.
青少年和年轻成年人（AYAs）参与临床试验的比例低于较年轻或较年长的癌症患者。需要采用多种方法来改变政策和实践，以改善这一统计数据。本文研究了增加向三种中心转诊的可能性，这些中心已知有相对较高的 AYA 参与率：儿科癌症中心、AYA 肿瘤学计划和美国国家癌症研究所指定的癌症中心。改变转诊模式存在合理的挑战，需要进行更多的研究，并对诊断 AYA 的人员进行教育。
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