Hsu Li-Chi, Chang Feng-Chi, Teng Michael Mu-Huo, Chern Chang-Ming, Wong Wen-Jang
Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC.
National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC; Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
J Chin Med Assoc. 2014 Aug;77(8):403-8. doi: 10.1016/j.jcma.2014.05.005. Epub 2014 Jul 12.
Little is known about the impact of severe carotid stenosis on health-related quality of life (HRQoL). The aim of this study was to assess the effects of carotid stenting (CAS) on HRQoL in dizzy patients with carotid stenosis.
Patients with symptomatic (≥60%) or asymptomatic (≥80%) severe carotid stenosis and who complained of dizziness and received CAS were recruited. Two HRQoL questionnaires-a generic survey, the 36-item Short-Form Health Survey and a disease-specific instrument, the Dizziness Handicap Inventory-served as outcome measures. Patients were followed 1 week prior to CAS and 6 months postprocedurally.
CAS was performed in 178 consecutive patients, 61 of whom complained of dizziness. Forty-one patients (67.2%, 34 male; mean age, 73.3 ± 10.5 years; range, 47-87 years) completed the study. Twenty asymptomatic volunteers (17 male; mean age, 70.3 ± 9.3 years; range, 54-84 years) served as normal controls. Compared to controls, patients tallied lower scores in the overall total and three subscales (physical, functional, and emotional) of the Dizziness Handicap Inventory (p < 0.01). Similar findings were noted in seven out of eight domains of the 36-item Short-Form Health Survey score. After 6 months, CAS resulted in significantly improved HRQoL (role physical, bodily pain, general health, social function, and role emotional) in these patients.
CAS resulted in improved HRQoL in patients with severe carotid stenosis who experienced dizziness.
关于重度颈动脉狭窄对健康相关生活质量(HRQoL)的影响,人们了解甚少。本研究的目的是评估颈动脉支架置入术(CAS)对有头晕症状的颈动脉狭窄患者健康相关生活质量的影响。
招募有症状(≥60%)或无症状(≥80%)的重度颈动脉狭窄且主诉头晕并接受CAS的患者。两项健康相关生活质量问卷——一项通用调查问卷,即36项简明健康调查,以及一项疾病特异性工具,即头晕残障量表——作为结局指标。在CAS术前1周和术后6个月对患者进行随访。
连续178例患者接受了CAS,其中61例主诉头晕。41例患者(67.2%,34例男性;平均年龄73.3±10.5岁;范围47 - 87岁)完成了研究。20名无症状志愿者(17例男性;平均年龄70.3±9.3岁;范围54 - 84岁)作为正常对照。与对照组相比,患者在头晕残障量表的总体总分及三个子量表(身体、功能和情感)上得分较低(p < 0.01)。在36项简明健康调查评分的八个领域中的七个领域也发现了类似结果。6个月后,CAS使这些患者的健康相关生活质量(角色身体、身体疼痛、总体健康、社会功能和角色情感)得到显著改善。
CAS使有头晕症状的重度颈动脉狭窄患者的健康相关生活质量得到改善。