阿司匹林对林奇综合征相关结直肠癌的影响。
Effects of aspirin on colorectal cancer related to lynch syndrome.
作者信息
Beck Sarah Leilani
机构信息
Binghamton Gastroenterology Associates, Binghamton, New York.
出版信息
J Adv Pract Oncol. 2012 Nov;3(6):395-8.
Abstract
This article is a review of "Long-term effects of aspirin on cancer risk in carriers of hereditary colorectal cancer: An analysis from the CAPP2 randomised controlled trial" by Burn et al. (2011), Lancet, 378, 2081-2087. For another perspective on the Burn et al. article as well as a discussion of challenges faced when interpreting a large prospective trial, please see the related article by Rita Wickham.
摘要
本文是对Burn等人（2011年）发表于《柳叶刀》（第378卷，2081 - 2087页）的文章《阿司匹林对遗传性结直肠癌携带者癌症风险的长期影响：CAPP2随机对照试验分析》的综述。关于Burn等人文章的另一种观点以及解读大型前瞻性试验时面临的挑战的讨论，请参阅Rita Wickham的相关文章。
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本文引用的文献
1
Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial.
Lancet. 2011 Dec 17;378(9809):2081-7. doi: 10.1016/S0140-6736(11)61049-0. Epub 2011 Oct 27.
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Aspirin and colorectal cancer prevention in Lynch syndrome.
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Aspirin suppresses the mutator phenotype associated with hereditary nonpolyposis colorectal cancer by genetic selection.
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