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用于创伤性脑损伤的CogSMART代偿性认知训练:1年以上的效果

CogSMART Compensatory Cognitive Training for Traumatic Brain Injury: Effects Over 1 Year.

作者信息

Twamley Elizabeth W, Thomas Kelsey R, Gregory Amber M, Jak Amy J, Bondi Mark W, Delis Dean C, Lohr James B

机构信息

Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego, California (Drs Twamley, Jak, Delis, and Lohr); Department of Psychiatry, University of California, San Diego, La Jolla, California (Drs Twamley, Jak, Bondi, and Lohr); Department of Clinical and Health Psychology, University of Florida, Gainesville (Ms Thomas); Department of Psychology, The University of Alabama at Birmingham, Birmingham (Ms Gregory); Psychology Service, VA San Diego Healthcare System, San Diego, California (Drs Jak and Bondi).

出版信息

J Head Trauma Rehabil. 2015 Nov-Dec;30(6):391-401. doi: 10.1097/HTR.0000000000000076.

Abstract

OBJECTIVE

There are very few evidence-based treatments for individuals with mild to moderate traumatic brain injuries. We developed and tested a 12-week, manualized, compensatory cognitive training intervention, Cognitive Symptom Management and Rehabilitation Therapy (CogSMART), which targeted postconcussive symptom management, prospective memory, attention, learning/memory, and executive functioning. The intervention focused on psychoeducation and compensatory strategies such as calendar use, self-talk, note taking, and a 6-step problem-solving method.

SETTING

VA Healthcare System.

PARTICIPANTS

A total of 50 Veterans with mild to moderate traumatic brain injuries receiving supported employment.

DESIGN

Twelve-month randomized controlled trial with participants assigned to receive CogSMART or additional supported employment sessions for the first 12 weeks. Outcome assessments were administered at baseline and 3, 6, and 12 months.

MAIN MEASURES

Assessments measured postconcussive symptoms, neuropsychological performance, functional capacity, psychiatric symptom severity, quality of life, and weeks worked during the 12-month trial.

RESULTS

Hierarchical linear modeling analyses using all 4 time points demonstrated significant CogSMART-associated reductions in postconcussive symptoms (r = -0.28, P = .026, d = 0.64) and improvements in prospective memory (r = 0.35, P = .031, d = 0.55) and quality of life (r = 0.34, P = .009, d = 1.0). The groups did not differ on weeks worked during the trial.

CONCLUSION

CogSMART has the potential to improve postconcussive symptoms, cognitive performance, and self-rated quality of life in individuals with mild to moderate traumatic brain injuries.

摘要

目的

对于轻至中度创伤性脑损伤患者,基于证据的治疗方法非常少。我们开发并测试了一种为期12周、手册化的代偿性认知训练干预措施,即认知症状管理与康复疗法(CogSMART),该疗法针对脑震荡后症状管理、前瞻性记忆、注意力、学习/记忆和执行功能。干预措施侧重于心理教育和代偿策略,如使用日历、自我对话、做笔记以及一种六步问题解决方法。

设置

退伍军人医疗保健系统。

参与者

共有50名患有轻至中度创伤性脑损伤且正在接受支持性就业服务的退伍军人。

设计

为期12个月的随机对照试验,参与者在最初12周被分配接受CogSMART或额外的支持性就业课程。在基线以及3个月、6个月和12个月时进行结果评估。

主要测量指标

评估脑震荡后症状、神经心理表现、功能能力、精神症状严重程度、生活质量以及12个月试验期间的工作周数。

结果

使用所有4个时间点进行的分层线性模型分析表明,CogSMART与脑震荡后症状的显著减轻(r = -0.28,P = 0.026,d = 0.64)、前瞻性记忆的改善(r = 0.35,P = 0.031,d = 0.55)以及生活质量的提高(r = 0.34,P = 0.009,d = 1.0)相关。两组在试验期间的工作周数上没有差异。

结论

CogSMART有可能改善轻至中度创伤性脑损伤患者的脑震荡后症状、认知表现和自评生活质量。

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