2013年，北京，由A6型柯萨奇病毒引起的手足口病。
Hand, foot and mouth disease caused by coxsackievirus A6, Beijing, 2013.
作者信息
Hongyan Gu, Chengjie Ma, Qiaozhi Yang, Wenhao Hua, Juan Li, Lin Pang, Yanli Xu, Hongshan Wei, Xingwang Li
机构信息
From the *Beijing Ditan Hospital, Peking University Teaching Hospital, Beijing, China; †Beijing Ditan Hospital, Capital Medical University, Beijing, China; and ‡Liaocheng City Hospital, Liaocheng, Shandong, China.
出版信息
Pediatr Infect Dis J. 2014 Dec;33(12):1302-3. doi: 10.1097/INF.0000000000000467.
Specimens and clinical data were collected from 243 hand, foot and mouth disease patients in Beijing in 2013. In total, 130 stool specimens were genotyped for enterovirus. Hand, foot and mouth disease was mainly detected in suburban areas and at the edges of urban areas between May and August. Coxsackievirus (CV) A6 replaced enterovirus (EV) 71 and CVA16, becoming the main causative agent of hand, foot and mouth disease. CVA6 infection led to significantly reduced fever duration and glucose levels compared with EV71 infection.
2013年，从北京的243例手足口病患者中收集了标本和临床数据。总共对130份粪便标本进行了肠道病毒基因分型。手足口病主要在5月至8月期间在郊区和市区边缘被检测到。柯萨奇病毒（CV）A6取代肠道病毒（EV）71和CVA16，成为手足口病的主要病原体。与EV71感染相比，CVA6感染导致发热持续时间和血糖水平显著降低。
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