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原发性脑黑素细胞瘤的管理与预后。一例病例报告及系统评价。

Management and prognosis of primary cerebral melanocytic tumors. A case report and systematic review.

作者信息

Splavski Bruno, Muzevic Dario, Kovacevic Marko, Splavski Brano, Bajek Goran

机构信息

Department of Neurosurgery, Osijek Clinical Hospital Centre, Osijek, Croatia.

Division of Ophthalmology, Osijek Clinical Hospital Centre, Osijek, Croatia.

出版信息

J Neurol Surg A Cent Eur Neurosurg. 2015 Mar;76(2):144-8. doi: 10.1055/s-0034-1371514. Epub 2014 Jul 21.

Abstract

Primary melanocytic cerebral tumors form a spectrum of different lesions that range from benign to extremely malignant, such as an intracranial melanoma. This article points out some characteristics of primary melanocytic cerebral tumors and discusses their management and prognosis, based on a systematic literature review and a case of primary cerebral malignant melanoma.Because the biological characteristics of primary melanocytic cerebral tumors remain unclear, it appears that total surgical resection of the tumor followed by oncologic treatment is the mainstay of the management. The prognosis still depends on the degree of malignancy.

摘要

原发性黑素细胞性脑肿瘤构成了一系列不同的病变,其范围从良性到极恶性,例如颅内黑色素瘤。本文基于系统的文献综述和一例原发性脑恶性黑色素瘤病例,指出了原发性黑素细胞性脑肿瘤的一些特征,并讨论了其治疗和预后。由于原发性黑素细胞性脑肿瘤的生物学特性仍不清楚,肿瘤全切后进行肿瘤治疗似乎是主要的治疗方法。预后仍然取决于恶性程度。

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